Nipping at cardiac remodeling

Russell S. Whelan; Kartik Mani; Richard N. Kitsis

doi:10.1172/JCI33706

Nipping at cardiac remodeling

Russell S. Whelan, Kartik Mani, Richard N. Kitsis

Medicine

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Much of the mortality following myocardial infarction results from remodeling of the heart after the acute ischemic event. Cardiomyocyte apoptosis has been thought to play a key role in this remodeling process. In this issue of the JCI, Diwan and colleagues present evidence that Bnip3, a proapoptotic Bcl2 family protein, mediates cardiac enlargement, reshaping, and dysfunction in mice without influencing infarct size (see the related article beginning on page 2825).

Original language	English (US)
Pages (from-to)	2751-2753
Number of pages	3
Journal	Journal of Clinical Investigation
Volume	117
Issue number	10
DOIs	https://doi.org/10.1172/JCI33706
State	Published - Oct 1 2007

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1172/JCI33706

Cite this

@article{7b24a626c53246caa210aeea568f44db,

title = "Nipping at cardiac remodeling",

abstract = "Much of the mortality following myocardial infarction results from remodeling of the heart after the acute ischemic event. Cardiomyocyte apoptosis has been thought to play a key role in this remodeling process. In this issue of the JCI, Diwan and colleagues present evidence that Bnip3, a proapoptotic Bcl2 family protein, mediates cardiac enlargement, reshaping, and dysfunction in mice without influencing infarct size (see the related article beginning on page 2825).",

author = "Whelan, {Russell S.} and Kartik Mani and Kitsis, {Richard N.}",

year = "2007",

month = oct,

day = "1",

doi = "10.1172/JCI33706",

language = "English (US)",

volume = "117",

pages = "2751--2753",

journal = "Journal of Clinical Investigation",

issn = "0021-9738",

publisher = "The American Society for Clinical Investigation",

number = "10",

}

TY - JOUR

T1 - Nipping at cardiac remodeling

AU - Whelan, Russell S.

AU - Mani, Kartik

AU - Kitsis, Richard N.

PY - 2007/10/1

Y1 - 2007/10/1

N2 - Much of the mortality following myocardial infarction results from remodeling of the heart after the acute ischemic event. Cardiomyocyte apoptosis has been thought to play a key role in this remodeling process. In this issue of the JCI, Diwan and colleagues present evidence that Bnip3, a proapoptotic Bcl2 family protein, mediates cardiac enlargement, reshaping, and dysfunction in mice without influencing infarct size (see the related article beginning on page 2825).

AB - Much of the mortality following myocardial infarction results from remodeling of the heart after the acute ischemic event. Cardiomyocyte apoptosis has been thought to play a key role in this remodeling process. In this issue of the JCI, Diwan and colleagues present evidence that Bnip3, a proapoptotic Bcl2 family protein, mediates cardiac enlargement, reshaping, and dysfunction in mice without influencing infarct size (see the related article beginning on page 2825).

UR - http://www.scopus.com/inward/record.url?scp=34948820283&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34948820283&partnerID=8YFLogxK

U2 - 10.1172/JCI33706

DO - 10.1172/JCI33706

M3 - Review article

C2 - 17909620

AN - SCOPUS:34948820283

SN - 0021-9738

VL - 117

SP - 2751

EP - 2753

JO - Journal of Clinical Investigation

JF - Journal of Clinical Investigation

IS - 10

ER -

Nipping at cardiac remodeling

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this