Nipping at cardiac remodeling

Russell S. Whelan, Kartik Mani, Richard N. Kitsis

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Much of the mortality following myocardial infarction results from remodeling of the heart after the acute ischemic event. Cardiomyocyte apoptosis has been thought to play a key role in this remodeling process. In this issue of the JCI, Diwan and colleagues present evidence that Bnip3, a proapoptotic Bcl2 family protein, mediates cardiac enlargement, reshaping, and dysfunction in mice without influencing infarct size (see the related article beginning on page 2825).

Original languageEnglish (US)
Pages (from-to)2751-2753
Number of pages3
JournalJournal of Clinical Investigation
Volume117
Issue number10
DOIs
StatePublished - Oct 1 2007

Fingerprint

Cardiac Myocytes
Myocardial Infarction
Apoptosis
Mortality
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nipping at cardiac remodeling. / Whelan, Russell S.; Mani, Kartik; Kitsis, Richard N.

In: Journal of Clinical Investigation, Vol. 117, No. 10, 01.10.2007, p. 2751-2753.

Research output: Contribution to journalArticle

Whelan, Russell S. ; Mani, Kartik ; Kitsis, Richard N. / Nipping at cardiac remodeling. In: Journal of Clinical Investigation. 2007 ; Vol. 117, No. 10. pp. 2751-2753.
@article{7b24a626c53246caa210aeea568f44db,
title = "Nipping at cardiac remodeling",
abstract = "Much of the mortality following myocardial infarction results from remodeling of the heart after the acute ischemic event. Cardiomyocyte apoptosis has been thought to play a key role in this remodeling process. In this issue of the JCI, Diwan and colleagues present evidence that Bnip3, a proapoptotic Bcl2 family protein, mediates cardiac enlargement, reshaping, and dysfunction in mice without influencing infarct size (see the related article beginning on page 2825).",
author = "Whelan, {Russell S.} and Kartik Mani and Kitsis, {Richard N.}",
year = "2007",
month = "10",
day = "1",
doi = "10.1172/JCI33706",
language = "English (US)",
volume = "117",
pages = "2751--2753",
journal = "Journal of Clinical Investigation",
issn = "0021-9738",
publisher = "The American Society for Clinical Investigation",
number = "10",

}

TY - JOUR

T1 - Nipping at cardiac remodeling

AU - Whelan, Russell S.

AU - Mani, Kartik

AU - Kitsis, Richard N.

PY - 2007/10/1

Y1 - 2007/10/1

N2 - Much of the mortality following myocardial infarction results from remodeling of the heart after the acute ischemic event. Cardiomyocyte apoptosis has been thought to play a key role in this remodeling process. In this issue of the JCI, Diwan and colleagues present evidence that Bnip3, a proapoptotic Bcl2 family protein, mediates cardiac enlargement, reshaping, and dysfunction in mice without influencing infarct size (see the related article beginning on page 2825).

AB - Much of the mortality following myocardial infarction results from remodeling of the heart after the acute ischemic event. Cardiomyocyte apoptosis has been thought to play a key role in this remodeling process. In this issue of the JCI, Diwan and colleagues present evidence that Bnip3, a proapoptotic Bcl2 family protein, mediates cardiac enlargement, reshaping, and dysfunction in mice without influencing infarct size (see the related article beginning on page 2825).

UR - http://www.scopus.com/inward/record.url?scp=34948820283&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34948820283&partnerID=8YFLogxK

U2 - 10.1172/JCI33706

DO - 10.1172/JCI33706

M3 - Article

VL - 117

SP - 2751

EP - 2753

JO - Journal of Clinical Investigation

JF - Journal of Clinical Investigation

SN - 0021-9738

IS - 10

ER -