Nuovi sistemi per la prevenzione del rischio cardioembolico in pazienti con fibrillazione atriale: Una revisione sistematica della letteratura sulla chiusura percutanea dell'auricola sinistra

Translated title of the contribution: New systems for the prevention of cardioembolic risk in patients with atrial fibrillation: A systematic review of the literature on percutaneous left atrial appendage closure

Paolo Danna, Antonio Sagone, Riccardo Proietti, Andrea Arensi, Maurizio Viecca, Pasquale Santangeli, Luigi Di Biase, Andrea Natale

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Atrial fibrillation (AF) is the most common cardiac arrhythmia. The mortality rate of patients with AF is doubled as compared to non-fibrillating controls. The most relevant complication of AF is a major increase in the risk of stroke. The gold standard in reducing cerebrovascular events in AF is warfarin therapy, which is not free from contraindications and limitations. The left atrial appendage (LAA) is the main source of emboli causing stroke in AF. LAA closure is a seducing approach to stroke risk reduction in AF without anticoagulation. Since 1949, heart surgeons have performed LAA closure or amputation in patients with AF. Percutaneous endovascular LAA closure is a new, less invasive, technique to reach the goal. Several devices have been used to perform this intervention, and the results of published trials are encouraging in terms of effectiveness and relative safety of this attractive technique. In this review we examine the published trials and data on percutaneous LAA closure, with particular attention to the risks and benefits of this procedure.

Translated title of the contributionNew systems for the prevention of cardioembolic risk in patients with atrial fibrillation: A systematic review of the literature on percutaneous left atrial appendage closure
Original languageItalian
Pages (from-to)571-582
Number of pages12
JournalGiornale Italiano di Cardiologia
Volume13
Issue number9
DOIs
StatePublished - Sep 1 2012
Externally publishedYes

Keywords

  • Atrial fibrillation
  • Left atrial appendage closure
  • Stroke

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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