@inbook{925fe07e36fb4ea3929f3e1087839819,
title = "New insights in cardiac calcium handling and excitation-contraction coupling",
abstract = "Excitation-contraction (EC) coupling denotes the conversion of electric stimulus in mechanic output in contractile cells. Several studies have demonstrated that calcium (Ca2+) plays a pivotal role in this process. Here we present a comprehensive and updated description of the main systems involved in cardiac Ca2+ handling that ensure a functional EC coupling and their pathological alterations, mainly related to heart failure.",
keywords = "Calcium, Contraction, Heart Failure, Mitochondria, RyR, SerCa",
author = "Jessica Gambardella and Bruno Trimarco and Guido Iaccarino and Gaetano Santulli",
note = "Publisher Copyright: {\textcopyright} 2017, Springer International Publishing AG.",
year = "2018",
doi = "10.1007/5584_2017_106",
language = "English (US)",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer New York LLC",
pages = "373--385",
booktitle = "Advances in Experimental Medicine and Biology",
}