TY - JOUR
T1 - Neurotoxicity of e-cigarettes
AU - Ruszkiewicz, Joanna A.
AU - Zhang, Ziyan
AU - Gonçalves, Filipe Marques
AU - Tizabi, Yousef
AU - Zelikoff, Judith T.
AU - Aschner, Michael
N1 - Publisher Copyright:
© 2020 Elsevier Ltd
PY - 2020/4
Y1 - 2020/4
N2 - It appears that electronic cigarettes (EC) are a less harmful alternative to conventional cigarette (CC) smoking, as they generate substantially lower levels of harmful carcinogens and other toxic compounds. Thus, switching from CC to EC may be beneficial for smokers. However, recent accounts of EC- or vaping-associated lung injury (EVALI) has raised concerns regarding their adverse health effects. Additionally, the increasing popularity of EC among vulnerable populations, such as adolescents and pregnant women, calls for further EC safety evaluation. In this state-of-the-art review, we provide an update on recent findings regarding the neurological effects induced by EC exposure. Moreover, we discuss possible neurotoxic effects of nicotine and numerous other chemicals which are inherent both to e-liquids and EC aerosols. We conclude that in recognizing pertinent issues associated with EC usage, both government and scientific researchers must address this public health issue with utmost urgency.
AB - It appears that electronic cigarettes (EC) are a less harmful alternative to conventional cigarette (CC) smoking, as they generate substantially lower levels of harmful carcinogens and other toxic compounds. Thus, switching from CC to EC may be beneficial for smokers. However, recent accounts of EC- or vaping-associated lung injury (EVALI) has raised concerns regarding their adverse health effects. Additionally, the increasing popularity of EC among vulnerable populations, such as adolescents and pregnant women, calls for further EC safety evaluation. In this state-of-the-art review, we provide an update on recent findings regarding the neurological effects induced by EC exposure. Moreover, we discuss possible neurotoxic effects of nicotine and numerous other chemicals which are inherent both to e-liquids and EC aerosols. We conclude that in recognizing pertinent issues associated with EC usage, both government and scientific researchers must address this public health issue with utmost urgency.
KW - Brain
KW - Electronic cigarette
KW - Neurodevelopment
KW - Neurotoxicity
KW - Vaping
KW - e-cigarette
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U2 - 10.1016/j.fct.2020.111245
DO - 10.1016/j.fct.2020.111245
M3 - Review article
C2 - 32145355
AN - SCOPUS:85081033575
SN - 0278-6915
VL - 138
JO - Food and Chemical Toxicology
JF - Food and Chemical Toxicology
M1 - 111245
ER -