Neurotoxic chemical exposure scenarios and suggested solutions

H. H. Schaumberg, Joseph C. Arezzo, D. A. Otto, D. A. Eckerman

Research output: Contribution to journalArticle

Abstract

This manuscript reports the results of a problem-solving exercise presented to participants at a Workshop on Neurotoxicology Testing in Human Populations held in Rougemont, North Carolina in October, 1983. Response recommendations are the consensus of workshop participants. These are not comprehensive or definitive solutions and should be interpreted with caution. Each exposure scenario represents a 'real world' situation previously encountered by neurologists and epidemiologists. Ideally, a toxin affects a single, easily tested modality early in the illness before producing a complex neurological syndrome. Unfortunately this rarely happens; difficult choices and compromises about testing are usually necessary. At the end of each scenario likely areas of early subtle dysfunction were discussed and possible testing methods were outlined. Working participants were instructed to comment on the approach to the scenarios and to add to or dispute the proposed tests. It is clear that there are no right or wrong answers; however, the participants were urged to try to reach some sort of consensus. In each instance paricipants assumed that they were being notified by the company and not by a state or federal agency, and were to determine what would be most reasonable and effective way to offer help or obtain outside assistance in these situations.

Original languageEnglish (US)
Pages (from-to)351-353
Number of pages3
JournalNeurobehavioral Toxicology and Teratology
Volume7
Issue number4
StatePublished - 1985

Fingerprint

Consensus Development Conferences
Dissent and Disputes
Consensus
Exercise
Education
Testing
Population
Epidemiologists
Neurologists
Industry

ASJC Scopus subject areas

  • Embryology
  • Toxicology
  • Neuropsychology and Physiological Psychology

Cite this

Neurotoxic chemical exposure scenarios and suggested solutions. / Schaumberg, H. H.; Arezzo, Joseph C.; Otto, D. A.; Eckerman, D. A.

In: Neurobehavioral Toxicology and Teratology, Vol. 7, No. 4, 1985, p. 351-353.

Research output: Contribution to journalArticle

Schaumberg, HH, Arezzo, JC, Otto, DA & Eckerman, DA 1985, 'Neurotoxic chemical exposure scenarios and suggested solutions', Neurobehavioral Toxicology and Teratology, vol. 7, no. 4, pp. 351-353.
Schaumberg, H. H. ; Arezzo, Joseph C. ; Otto, D. A. ; Eckerman, D. A. / Neurotoxic chemical exposure scenarios and suggested solutions. In: Neurobehavioral Toxicology and Teratology. 1985 ; Vol. 7, No. 4. pp. 351-353.
@article{e0dfbffb051c40fbb6d2213b86117df9,
title = "Neurotoxic chemical exposure scenarios and suggested solutions",
abstract = "This manuscript reports the results of a problem-solving exercise presented to participants at a Workshop on Neurotoxicology Testing in Human Populations held in Rougemont, North Carolina in October, 1983. Response recommendations are the consensus of workshop participants. These are not comprehensive or definitive solutions and should be interpreted with caution. Each exposure scenario represents a 'real world' situation previously encountered by neurologists and epidemiologists. Ideally, a toxin affects a single, easily tested modality early in the illness before producing a complex neurological syndrome. Unfortunately this rarely happens; difficult choices and compromises about testing are usually necessary. At the end of each scenario likely areas of early subtle dysfunction were discussed and possible testing methods were outlined. Working participants were instructed to comment on the approach to the scenarios and to add to or dispute the proposed tests. It is clear that there are no right or wrong answers; however, the participants were urged to try to reach some sort of consensus. In each instance paricipants assumed that they were being notified by the company and not by a state or federal agency, and were to determine what would be most reasonable and effective way to offer help or obtain outside assistance in these situations.",
author = "Schaumberg, {H. H.} and Arezzo, {Joseph C.} and Otto, {D. A.} and Eckerman, {D. A.}",
year = "1985",
language = "English (US)",
volume = "7",
pages = "351--353",
journal = "Neurotoxicology and Teratology",
issn = "0892-0362",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - Neurotoxic chemical exposure scenarios and suggested solutions

AU - Schaumberg, H. H.

AU - Arezzo, Joseph C.

AU - Otto, D. A.

AU - Eckerman, D. A.

PY - 1985

Y1 - 1985

N2 - This manuscript reports the results of a problem-solving exercise presented to participants at a Workshop on Neurotoxicology Testing in Human Populations held in Rougemont, North Carolina in October, 1983. Response recommendations are the consensus of workshop participants. These are not comprehensive or definitive solutions and should be interpreted with caution. Each exposure scenario represents a 'real world' situation previously encountered by neurologists and epidemiologists. Ideally, a toxin affects a single, easily tested modality early in the illness before producing a complex neurological syndrome. Unfortunately this rarely happens; difficult choices and compromises about testing are usually necessary. At the end of each scenario likely areas of early subtle dysfunction were discussed and possible testing methods were outlined. Working participants were instructed to comment on the approach to the scenarios and to add to or dispute the proposed tests. It is clear that there are no right or wrong answers; however, the participants were urged to try to reach some sort of consensus. In each instance paricipants assumed that they were being notified by the company and not by a state or federal agency, and were to determine what would be most reasonable and effective way to offer help or obtain outside assistance in these situations.

AB - This manuscript reports the results of a problem-solving exercise presented to participants at a Workshop on Neurotoxicology Testing in Human Populations held in Rougemont, North Carolina in October, 1983. Response recommendations are the consensus of workshop participants. These are not comprehensive or definitive solutions and should be interpreted with caution. Each exposure scenario represents a 'real world' situation previously encountered by neurologists and epidemiologists. Ideally, a toxin affects a single, easily tested modality early in the illness before producing a complex neurological syndrome. Unfortunately this rarely happens; difficult choices and compromises about testing are usually necessary. At the end of each scenario likely areas of early subtle dysfunction were discussed and possible testing methods were outlined. Working participants were instructed to comment on the approach to the scenarios and to add to or dispute the proposed tests. It is clear that there are no right or wrong answers; however, the participants were urged to try to reach some sort of consensus. In each instance paricipants assumed that they were being notified by the company and not by a state or federal agency, and were to determine what would be most reasonable and effective way to offer help or obtain outside assistance in these situations.

UR - http://www.scopus.com/inward/record.url?scp=0022341653&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022341653&partnerID=8YFLogxK

M3 - Article

C2 - 4058644

AN - SCOPUS:0022341653

VL - 7

SP - 351

EP - 353

JO - Neurotoxicology and Teratology

JF - Neurotoxicology and Teratology

SN - 0892-0362

IS - 4

ER -