Neuron loss in the nucleus basalis of meynert in parkinsonism‐dementia complex of Guam

Imaharu Nakano, Asao Hirano

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Abstract

The nucleus basalis of Meynert, which supplies diffuse cholinergic fibers to the cerebral neocortex, was investigated in two cases of parkinsonism‐dementia complex of Guam (PDG). The nucleus basalis of the two PDG patients showed extensive neuron loss when compared with age‐matched non‐Guamanian controls, suggesting the necessity of investigating activity of cholinergic enzymes in the brains of patients with PDG.

Original languageEnglish (US)
Pages (from-to)87-91
Number of pages5
JournalAnnals of Neurology
Volume13
Issue number1
DOIs
Publication statusPublished - Jan 1983

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ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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