Neuron loss in the nucleus basalis of meynert in parkinsonism‐dementia complex of Guam

Imaharu Nakano, Asao Hirano

Research output: Contribution to journalArticle

84 Scopus citations


The nucleus basalis of Meynert, which supplies diffuse cholinergic fibers to the cerebral neocortex, was investigated in two cases of parkinsonism‐dementia complex of Guam (PDG). The nucleus basalis of the two PDG patients showed extensive neuron loss when compared with age‐matched non‐Guamanian controls, suggesting the necessity of investigating activity of cholinergic enzymes in the brains of patients with PDG.

Original languageEnglish (US)
Pages (from-to)87-91
Number of pages5
JournalAnnals of Neurology
Issue number1
Publication statusPublished - Jan 1983


ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this