Neuron loss in the nucleus basalis of Meynert in parkinsonism-dementia complex of Guam

I. Nakano, A. Hirano

Research output: Contribution to journalArticle

84 Citations (Scopus)

Abstract

The nucleus basalis of Meynert, which supplies diffuse cholinergic fibers to the cerebral neocortex, was investigated in two cases of parkinsonism-dementia complex of Guam (PDG). The nucleus basalis of the two PDG patients showed extensive neuron loss when compared with age-matched non-Guamanian controls, suggesting the necessity of investigating activity of cholinergic enzymes in the brains of patients with PDG.

Original languageEnglish (US)
Pages (from-to)87-91
Number of pages5
JournalAnnals of Neurology
Volume13
Issue number1
StatePublished - 1983

Fingerprint

Guam
Basal Nucleus of Meynert
Parkinsonian Disorders
Dementia
Neurons
Cholinergic Fibers
Neocortex
Cholinergic Agents
Brain
Enzymes

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Neuron loss in the nucleus basalis of Meynert in parkinsonism-dementia complex of Guam. / Nakano, I.; Hirano, A.

In: Annals of Neurology, Vol. 13, No. 1, 1983, p. 87-91.

Research output: Contribution to journalArticle

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