Neural Circuit Mechanisms Underlying Emotional Regulation of Homeostatic Feeding

Patrick Sweeney, Yunlei Yang

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

The neural circuits controlling feeding and emotional behaviors are intricately and reciprocally connected. Recent technological developments, including cell type-specific optogenetic and chemogenetic approaches, allow functional characterization of genetically defined cell populations and neural circuits in feeding and emotional processes. Here we review recent studies that have utilized circuit-based manipulations to decipher the functional interactions between neural circuits controlling feeding and those controlling emotional processes. Specifically, we highlight newly described neural circuit interactions between classical emotion-related brain regions, such as the hippocampus and amygdala, and homeostatic feeding circuitry in the arcuate nucleus and lateral hypothalamus (LH). Together these circuits will provide a template for future studies to examine functional interactions between feeding and emotion.

Original languageEnglish (US)
Pages (from-to)437-448
Number of pages12
JournalTrends in Endocrinology and Metabolism
Volume28
Issue number6
DOIs
Publication statusPublished - Jun 1 2017
Externally publishedYes

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ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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