Neural Circuit Mechanisms Underlying Emotional Regulation of Homeostatic Feeding

Patrick Sweeney, Yunlei Yang

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

The neural circuits controlling feeding and emotional behaviors are intricately and reciprocally connected. Recent technological developments, including cell type-specific optogenetic and chemogenetic approaches, allow functional characterization of genetically defined cell populations and neural circuits in feeding and emotional processes. Here we review recent studies that have utilized circuit-based manipulations to decipher the functional interactions between neural circuits controlling feeding and those controlling emotional processes. Specifically, we highlight newly described neural circuit interactions between classical emotion-related brain regions, such as the hippocampus and amygdala, and homeostatic feeding circuitry in the arcuate nucleus and lateral hypothalamus (LH). Together these circuits will provide a template for future studies to examine functional interactions between feeding and emotion.

Original languageEnglish (US)
Pages (from-to)437-448
Number of pages12
JournalTrends in Endocrinology and Metabolism
Volume28
Issue number6
DOIs
StatePublished - Jun 1 2017
Externally publishedYes

Fingerprint

Emotions
Optogenetics
Lateral Hypothalamic Area
Arcuate Nucleus of Hypothalamus
Feeding Behavior
Amygdala
Hippocampus
Brain
Population

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Neural Circuit Mechanisms Underlying Emotional Regulation of Homeostatic Feeding. / Sweeney, Patrick; Yang, Yunlei.

In: Trends in Endocrinology and Metabolism, Vol. 28, No. 6, 01.06.2017, p. 437-448.

Research output: Contribution to journalReview article

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