Nativity differences in allostatic load by age, sex, and Hispanic background from the Hispanic Community Health Study/Study of Latinos

Christian R. Salazar, Garrett Strizich, Teresa E. Seeman, Carmen R. Isasi, Linda C. Gallo, Larissa M. Avilés-Santa, Jianwen Cai, Frank J. Penedo, William Arguelles, Anne E. Sanders, Richard B. Lipton, Robert C. Kaplan

Research output: Contribution to journalArticle

11 Scopus citations


Allostatic load (AL), an index of biological "wear and tear" on the body from cumulative exposure to stress, has been little studied in US Hispanics/Latinos. We investigated AL accumulation patterns by age, sex, and nativity in the Hispanic Community Health Study/Study of Latinos. We studied 15,830 Hispanic/Latinos of Mexican, Cuban, Dominican, Puerto Rican, Central and South American descent aged 18-74 years, 77% of whom were foreign-born. Consistent with the conceptualization of AL, we developed an index based upon 16 physiological markers that spanned the cardiometabolic, parasympathetic, and inflammatory systems. We computed mean adjusted AL scores using log-linear models across age-groups (18-44, 45-54, 55-74 years), by sex and nativity status. Among foreign-born individuals, differences in AL by duration of residence in the US (

Original languageEnglish (US)
Pages (from-to)416-424
Number of pages9
JournalSSM - Population Health
StatePublished - Dec 1 2016



  • Age patterns
  • Allostatic load
  • Hispanic ethnicity
  • Nativity
  • Physiological dysregulation

ASJC Scopus subject areas

  • Health(social science)
  • Public Health, Environmental and Occupational Health
  • Health Policy

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