Nanotechnology and the diagnosis of dermatological infectious disease

Karin Blecher Paz, Adam Friedman

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Despite advances in diagnostics and therapeutics, infectious diseases continue to be a major cause of morbidity and mortality, surpassing cardiovascular diseases and cancer. Accurate identification of causative pathogens is critical to prevent the spread of infectious diseases and to deliver appropriate and timely therapy. Various limitations ranging from cost to lengthy yield times of current diagnostic modalities highlight the need for new approaches. Nanotechnology represents an innovative direction offering many advantages for pathogen detection and identification. Through surface modifications, nanoparticles can be tailored to bind microbial surface markers, nucleic acids, and toxins. Combining these nanoparticles with both standard and developing detection technologies has led to the development of faster, more sensitive, and more economical diagnostic assays. This review will focus on the diagnostic advances that utilize fluorescent, metallic, and magnetic nanomaterials, highlighting their potential applications in the diagnosis of infectious dermatological conditions.

Original languageEnglish (US)
Pages (from-to)846-851
Number of pages6
JournalJournal of Drugs in Dermatology
Volume11
Issue number7
StatePublished - Jul 2012

Fingerprint

Nanotechnology
Nanoparticles
Communicable Diseases
Nanostructures
Nucleic Acids
Cardiovascular Diseases
Technology
Morbidity
Costs and Cost Analysis
Mortality
Therapeutics
Neoplasms
Direction compound

ASJC Scopus subject areas

  • Medicine(all)
  • Dermatology

Cite this

Nanotechnology and the diagnosis of dermatological infectious disease. / Blecher Paz, Karin; Friedman, Adam.

In: Journal of Drugs in Dermatology, Vol. 11, No. 7, 07.2012, p. 846-851.

Research output: Contribution to journalReview article

@article{8926be2307ce48cbab9c0757231a9a42,
title = "Nanotechnology and the diagnosis of dermatological infectious disease",
abstract = "Despite advances in diagnostics and therapeutics, infectious diseases continue to be a major cause of morbidity and mortality, surpassing cardiovascular diseases and cancer. Accurate identification of causative pathogens is critical to prevent the spread of infectious diseases and to deliver appropriate and timely therapy. Various limitations ranging from cost to lengthy yield times of current diagnostic modalities highlight the need for new approaches. Nanotechnology represents an innovative direction offering many advantages for pathogen detection and identification. Through surface modifications, nanoparticles can be tailored to bind microbial surface markers, nucleic acids, and toxins. Combining these nanoparticles with both standard and developing detection technologies has led to the development of faster, more sensitive, and more economical diagnostic assays. This review will focus on the diagnostic advances that utilize fluorescent, metallic, and magnetic nanomaterials, highlighting their potential applications in the diagnosis of infectious dermatological conditions.",
author = "{Blecher Paz}, Karin and Adam Friedman",
year = "2012",
month = "7",
language = "English (US)",
volume = "11",
pages = "846--851",
journal = "Journal of Drugs in Dermatology",
issn = "1545-9616",
publisher = "Journal of Drugs in Dermatology",
number = "7",

}

TY - JOUR

T1 - Nanotechnology and the diagnosis of dermatological infectious disease

AU - Blecher Paz, Karin

AU - Friedman, Adam

PY - 2012/7

Y1 - 2012/7

N2 - Despite advances in diagnostics and therapeutics, infectious diseases continue to be a major cause of morbidity and mortality, surpassing cardiovascular diseases and cancer. Accurate identification of causative pathogens is critical to prevent the spread of infectious diseases and to deliver appropriate and timely therapy. Various limitations ranging from cost to lengthy yield times of current diagnostic modalities highlight the need for new approaches. Nanotechnology represents an innovative direction offering many advantages for pathogen detection and identification. Through surface modifications, nanoparticles can be tailored to bind microbial surface markers, nucleic acids, and toxins. Combining these nanoparticles with both standard and developing detection technologies has led to the development of faster, more sensitive, and more economical diagnostic assays. This review will focus on the diagnostic advances that utilize fluorescent, metallic, and magnetic nanomaterials, highlighting their potential applications in the diagnosis of infectious dermatological conditions.

AB - Despite advances in diagnostics and therapeutics, infectious diseases continue to be a major cause of morbidity and mortality, surpassing cardiovascular diseases and cancer. Accurate identification of causative pathogens is critical to prevent the spread of infectious diseases and to deliver appropriate and timely therapy. Various limitations ranging from cost to lengthy yield times of current diagnostic modalities highlight the need for new approaches. Nanotechnology represents an innovative direction offering many advantages for pathogen detection and identification. Through surface modifications, nanoparticles can be tailored to bind microbial surface markers, nucleic acids, and toxins. Combining these nanoparticles with both standard and developing detection technologies has led to the development of faster, more sensitive, and more economical diagnostic assays. This review will focus on the diagnostic advances that utilize fluorescent, metallic, and magnetic nanomaterials, highlighting their potential applications in the diagnosis of infectious dermatological conditions.

UR - http://www.scopus.com/inward/record.url?scp=84866145635&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84866145635&partnerID=8YFLogxK

M3 - Review article

VL - 11

SP - 846

EP - 851

JO - Journal of Drugs in Dermatology

JF - Journal of Drugs in Dermatology

SN - 1545-9616

IS - 7

ER -