Nanoparticles guided drug delivery and imaging in gastric cancer

Ganji Purnachandra Nagaraju, Gowru Srivani, Begum Dariya, Gayathri Chalikonda, Batoul Farran, Santosh Kumar Behera, Afroz Alam, Mohammad Amjad Kamal

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

Gastric cancer represents a deadly malignancy worldwide, yet current therapeutic regimens remain ineffective. Nanoparticle (NP) -based solutions could allow the design of novel therapeutic methods to eliminate this fatal disease. NPs typically carry out a significant role in multifunctional, multimodal imaging, and drug delivery carriers. In the recent decade, they have emerged as candidate approaches for the design of novel treatment strategies. Tumor nanotherapeutics characteristically possess various distinct advantages compared to conventional anti-cancer medications, which suffer from nonspecific bio-distribution, low solubility, and poor bioavailability. In this review, we will discuss the application of NPs in diagnosis and controlled drug delivery in gastric cancer (GC). We will focus on various NPs-based strategies employed against GC.

Original languageEnglish (US)
Pages (from-to)69-76
Number of pages8
JournalSeminars in Cancer Biology
Volume69
DOIs
StatePublished - Feb 2021
Externally publishedYes

Keywords

  • Controlled drug delivery
  • Gastric cancer
  • Imaging
  • Nanoparticles
  • Nanotherapeutics

ASJC Scopus subject areas

  • Cancer Research

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