TY - JOUR
T1 - Nanoparticles guided drug delivery and imaging in gastric cancer
AU - Nagaraju, Ganji Purnachandra
AU - Srivani, Gowru
AU - Dariya, Begum
AU - Chalikonda, Gayathri
AU - Farran, Batoul
AU - Behera, Santosh Kumar
AU - Alam, Afroz
AU - Kamal, Mohammad Amjad
N1 - Publisher Copyright:
© 2020 Elsevier Ltd
PY - 2021/2
Y1 - 2021/2
N2 - Gastric cancer represents a deadly malignancy worldwide, yet current therapeutic regimens remain ineffective. Nanoparticle (NP) -based solutions could allow the design of novel therapeutic methods to eliminate this fatal disease. NPs typically carry out a significant role in multifunctional, multimodal imaging, and drug delivery carriers. In the recent decade, they have emerged as candidate approaches for the design of novel treatment strategies. Tumor nanotherapeutics characteristically possess various distinct advantages compared to conventional anti-cancer medications, which suffer from nonspecific bio-distribution, low solubility, and poor bioavailability. In this review, we will discuss the application of NPs in diagnosis and controlled drug delivery in gastric cancer (GC). We will focus on various NPs-based strategies employed against GC.
AB - Gastric cancer represents a deadly malignancy worldwide, yet current therapeutic regimens remain ineffective. Nanoparticle (NP) -based solutions could allow the design of novel therapeutic methods to eliminate this fatal disease. NPs typically carry out a significant role in multifunctional, multimodal imaging, and drug delivery carriers. In the recent decade, they have emerged as candidate approaches for the design of novel treatment strategies. Tumor nanotherapeutics characteristically possess various distinct advantages compared to conventional anti-cancer medications, which suffer from nonspecific bio-distribution, low solubility, and poor bioavailability. In this review, we will discuss the application of NPs in diagnosis and controlled drug delivery in gastric cancer (GC). We will focus on various NPs-based strategies employed against GC.
KW - Controlled drug delivery
KW - Gastric cancer
KW - Imaging
KW - Nanoparticles
KW - Nanotherapeutics
UR - http://www.scopus.com/inward/record.url?scp=85078045809&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85078045809&partnerID=8YFLogxK
U2 - 10.1016/j.semcancer.2020.01.006
DO - 10.1016/j.semcancer.2020.01.006
M3 - Review article
C2 - 31954835
AN - SCOPUS:85078045809
SN - 1044-579X
VL - 69
SP - 69
EP - 76
JO - Seminars in Cancer Biology
JF - Seminars in Cancer Biology
ER -
