N-butyl cyanoacrylate embolization using a detachable tip microcatheter: Initial experience

Srinivasan Paramasivam, David J. Altschul, Santiago Ortega-Gutiarrez, Johanna Fifi, Alejandro Berenstein

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Introduction Endovascular embolization of intracranial vascular malformations with N-butyl cyanoacrylate (nBCA) using a detachable tip microcatheter allows prolonged injection and decreases the risk of catheter retention. Methods Between March and December 2013, the Apollo 1.5 cm detachable tip microcatheter was used in five patients after being approved by both the Food and Drug Administration and the institutional review board as a compassionate use device. Nine pedicles were embolized and the follow-up ranged from 1 to 3 months. Results Five of the nine catheter tips detached. The length of reflux was not directly associated with the detachment of the distal tip. There were no cases of premature microcatheter detachment during navigation, manipulation with multiple microguidewire reintroduction and guidance. There was no leak of embolic agent at the detachment zone. Follow-up showed the detached tip to be stable without migration. Conclusions A detachable tip microcatheter offers an advance in the safety and effectiveness of nBCA embolization. Catheter retrieval becomes more controlled and less traumatic. Our initial experience is encouraging, and more experience is needed to categorically ascertain its safety and efficacy.

Original languageEnglish (US)
Pages (from-to)458-461
Number of pages4
JournalJournal of NeuroInterventional Surgery
Volume7
Issue number6
DOIs
StatePublished - Jun 1 2015
Externally publishedYes

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Enbucrilate
Catheters
Compassionate Use Trials
Safety
Vascular Malformations
Research Ethics Committees
United States Food and Drug Administration
Equipment and Supplies
Injections

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

N-butyl cyanoacrylate embolization using a detachable tip microcatheter : Initial experience. / Paramasivam, Srinivasan; Altschul, David J.; Ortega-Gutiarrez, Santiago; Fifi, Johanna; Berenstein, Alejandro.

In: Journal of NeuroInterventional Surgery, Vol. 7, No. 6, 01.06.2015, p. 458-461.

Research output: Contribution to journalArticle

Paramasivam, Srinivasan ; Altschul, David J. ; Ortega-Gutiarrez, Santiago ; Fifi, Johanna ; Berenstein, Alejandro. / N-butyl cyanoacrylate embolization using a detachable tip microcatheter : Initial experience. In: Journal of NeuroInterventional Surgery. 2015 ; Vol. 7, No. 6. pp. 458-461.
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