Myocardial wall velocity assessment by pulsed Doppler tissue imaging: Characteristic findings in normal subjects

Mario J. Garcia, Leonardo Rodriguez, Miguel Ares, Brian P. Griffin, Allan L. Klein, William J. Stewart, James D. Thomas

Research output: Contribution to journalArticle

227 Scopus citations


To validate the use of pulsed Doppler tissue imaging that measures myocardial wall velocities and to define the characteristics of these velocities in normal subjects, we obtained and compared the anteroseptal and posterior wall velocities in 24 volunteers with pulsed Doppler tissue imaging and digitized M-mode echocardiography. We also studied the relation between velocity components and hemodynamic events timed by standard Doppler flows. There was an excellent correlation between Doppler and M-mode-derived velocities (r = 0.95, p < 0.001), with higher reproducibility for Doppler (r= 0.99) than for M-mode (r = 0.95, p < 0.001). Biphasic velocities that were uniformly present during isovolumic contraction and relaxation were attributed to geometric changes due to asynchronous contraction and ventricular interdependence. We conclude that wall velocities obtained by pulsed Doppler tissue imaging are accurate and reproducible. This method may prove useful for studying the contractile and elastic properties of the myocardium.

Original languageEnglish (US)
Pages (from-to)648-656
Number of pages9
JournalAmerican heart journal
Issue number3
StatePublished - Jan 1 1996
Externally publishedYes


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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