Muscle Overactivity in the Upper Motor Neuron Syndrome: Conceptualizing a Treatment Plan and Establishing Meaningful Goals

Anne Felicia Ambrose, Tanya Verghese, Carolin Dohle, Jennifer Russo

Research output: Contribution to journalReview article


Spasticity is a major physical complication of many neurologic and traumatic conditions of the brain and spine and can lead to muscle contracture, joint stiffness, reduced range of movement, skin breakdown, and pain. The management of spasticity includes a range of pharmacologic and nonpharmacologic interventions, often used in combination to optimize outcomes. However, it is important to identify and prioritize the patient's and clinician's goals, in order to create common attainable goals. These goals should be reviewed and revised at regular intervals.

Original languageEnglish (US)
Pages (from-to)483-500
Number of pages18
JournalPhysical Medicine and Rehabilitation Clinics of North America
Issue number3
Publication statusPublished - Aug 2018



  • Goal setting
  • Muscle overactivity
  • Spasticity
  • Treatment goals

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

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