Murine leukemia virus: detection of unintegrated double stranded DNA forms of the provirus

A. M. Gianni, D. Smotkin, R. A. Weinberg

Research output: Contribution to journalArticle

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Abstract

Infection of JLS V9 (mouse bone marrow) cells with Moloney murine leukemia virus leads to appearance of virus specific DNA in the low molecular weight DNA fraction from infected cells. Most of this DNA is double stranded. Two discrete forms of double stranded DNA, both of molecular weight 6x106, have been characterized. One of these forms is closed circular, supercoiled DNA; the other form is a mixture of nicked circlar and linear DNA.

Original languageEnglish (US)
Pages (from-to)447-451
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume72
Issue number2
DOIs
Publication statusPublished - Jan 1 1975
Externally publishedYes

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ASJC Scopus subject areas

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