Multiple endocrine neoplasia type 1: Clinical manifestations and management

Anathea C. Powell, Steven K. Libutti

Research output: Chapter in Book/Report/Conference proceedingChapter

19 Scopus citations

Abstract

Multiple endocrine neoplasia type I (MEN-1) is an autosomal dominant syndrome associated with anterior pituitary, parathyroid, and enteropancreatic endocrine tumors as well as other endocrine and nonendocrine tumors [1]. MEN-1 is defined as the presence of two of three main MEN-1-related manifestations, or at least one manifestation plus a first degree relative with at least one MEN-1-related manifestation [1,2]. The estimated prevalence of MEN-1 ranges from 1 in 10,000 to 1 in 100,000 [3], with 43 and 94% penetrance of MEN-1 by ages 20 and 50, respectively [4].

Original languageEnglish (US)
Title of host publicationEndocrine Neoplasia
EditorsCord Sturgeon
Pages287-302
Number of pages16
DOIs
StatePublished - 2010

Publication series

NameCancer Treatment and Research
Volume153
ISSN (Print)0927-3042

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint

Dive into the research topics of 'Multiple endocrine neoplasia type 1: Clinical manifestations and management'. Together they form a unique fingerprint.

Cite this