Multiple arterial phase MRI of arterial hypervascular hepatic lesions: improved arterial phase capture and lesion enhancement

Nabia S. Ikram, Judy Yee, Stefanie Weinstein, Benjamin M. Yeh, Carlos U. Corvera, Alexander Monto, Thomas A. Hope

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose: To establish if triple-phase arterial imaging improves the detection of arterial phase hyperintense lesions based on arterial phase capture, motion artifact degradation, and lesion enhancement when compared to single-phase imaging. Materials and methods: Patients at risk for hepatocellular carcinoma were imaged at 3.0T. Seventy-three consecutive patients with a standard single-phase MRI and eighty-five consecutive patients were imaged using extracellular contrast with triple arterial phase MRI using three sequential accelerated acquisitions of 8 s. Arterial phase capture and image quality were qualitatively categorized. Forty single-phase and forty-four triple-phase studies contained arterially enhancing lesions > 1 cm with washout appearance. The contrast-to-noise ratio (CNR) of the lesions was calculated. We compared the differences in means with Student t-tests and those in arterial phase capture with a Chi squared test with Yates correction. Results: The triple-phase acquisitions captured the early or late arterial phases more frequently than did the single-phase acquisition (99% vs 86%; P value = 0.006). Triple-phase also provided greater number of patients with early or late arterial phase imaging without motion artifact (92% vs 79%, P-value = 0.05). The lesion analysis revealed increased maximum CNR in the triple-phase imaging (704.4) vs. single-phase imaging (517.2), P-value < 0.001. Conclusion: Triple-phase acquisition provides more robust arterial phase imaging for hepatic lesions, with increased lesion CNR, compared to standard single-phase arterial phase imaging.

Original languageEnglish (US)
Pages (from-to)870-876
Number of pages7
JournalAbdominal Radiology
Volume42
Issue number3
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

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Liver
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Hepatocellular Carcinoma
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Keywords

  • Arterial phase imaging
  • Hepatocellular carcinoma
  • Liver MRI
  • Respiratory motion

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

Cite this

Multiple arterial phase MRI of arterial hypervascular hepatic lesions : improved arterial phase capture and lesion enhancement. / Ikram, Nabia S.; Yee, Judy; Weinstein, Stefanie; Yeh, Benjamin M.; Corvera, Carlos U.; Monto, Alexander; Hope, Thomas A.

In: Abdominal Radiology, Vol. 42, No. 3, 01.03.2017, p. 870-876.

Research output: Contribution to journalArticle

Ikram, Nabia S. ; Yee, Judy ; Weinstein, Stefanie ; Yeh, Benjamin M. ; Corvera, Carlos U. ; Monto, Alexander ; Hope, Thomas A. / Multiple arterial phase MRI of arterial hypervascular hepatic lesions : improved arterial phase capture and lesion enhancement. In: Abdominal Radiology. 2017 ; Vol. 42, No. 3. pp. 870-876.
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N2 - Purpose: To establish if triple-phase arterial imaging improves the detection of arterial phase hyperintense lesions based on arterial phase capture, motion artifact degradation, and lesion enhancement when compared to single-phase imaging. Materials and methods: Patients at risk for hepatocellular carcinoma were imaged at 3.0T. Seventy-three consecutive patients with a standard single-phase MRI and eighty-five consecutive patients were imaged using extracellular contrast with triple arterial phase MRI using three sequential accelerated acquisitions of 8 s. Arterial phase capture and image quality were qualitatively categorized. Forty single-phase and forty-four triple-phase studies contained arterially enhancing lesions > 1 cm with washout appearance. The contrast-to-noise ratio (CNR) of the lesions was calculated. We compared the differences in means with Student t-tests and those in arterial phase capture with a Chi squared test with Yates correction. Results: The triple-phase acquisitions captured the early or late arterial phases more frequently than did the single-phase acquisition (99% vs 86%; P value = 0.006). Triple-phase also provided greater number of patients with early or late arterial phase imaging without motion artifact (92% vs 79%, P-value = 0.05). The lesion analysis revealed increased maximum CNR in the triple-phase imaging (704.4) vs. single-phase imaging (517.2), P-value < 0.001. Conclusion: Triple-phase acquisition provides more robust arterial phase imaging for hepatic lesions, with increased lesion CNR, compared to standard single-phase arterial phase imaging.

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