Multiple arterial phase MRI of arterial hypervascular hepatic lesions

improved arterial phase capture and lesion enhancement

Nabia S. Ikram, Judy Yee, Stefanie Weinstein, Benjamin M. Yeh, Carlos U. Corvera, Alexander Monto, Thomas A. Hope

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose: To establish if triple-phase arterial imaging improves the detection of arterial phase hyperintense lesions based on arterial phase capture, motion artifact degradation, and lesion enhancement when compared to single-phase imaging. Materials and methods: Patients at risk for hepatocellular carcinoma were imaged at 3.0T. Seventy-three consecutive patients with a standard single-phase MRI and eighty-five consecutive patients were imaged using extracellular contrast with triple arterial phase MRI using three sequential accelerated acquisitions of 8 s. Arterial phase capture and image quality were qualitatively categorized. Forty single-phase and forty-four triple-phase studies contained arterially enhancing lesions > 1 cm with washout appearance. The contrast-to-noise ratio (CNR) of the lesions was calculated. We compared the differences in means with Student t-tests and those in arterial phase capture with a Chi squared test with Yates correction. Results: The triple-phase acquisitions captured the early or late arterial phases more frequently than did the single-phase acquisition (99% vs 86%; P value = 0.006). Triple-phase also provided greater number of patients with early or late arterial phase imaging without motion artifact (92% vs 79%, P-value = 0.05). The lesion analysis revealed increased maximum CNR in the triple-phase imaging (704.4) vs. single-phase imaging (517.2), P-value < 0.001. Conclusion: Triple-phase acquisition provides more robust arterial phase imaging for hepatic lesions, with increased lesion CNR, compared to standard single-phase arterial phase imaging.

Original languageEnglish (US)
Pages (from-to)870-876
Number of pages7
JournalAbdominal Radiology
Volume42
Issue number3
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

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Noise
Liver
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Hepatocellular Carcinoma
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Keywords

  • Arterial phase imaging
  • Hepatocellular carcinoma
  • Liver MRI
  • Respiratory motion

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

Cite this

Multiple arterial phase MRI of arterial hypervascular hepatic lesions : improved arterial phase capture and lesion enhancement. / Ikram, Nabia S.; Yee, Judy; Weinstein, Stefanie; Yeh, Benjamin M.; Corvera, Carlos U.; Monto, Alexander; Hope, Thomas A.

In: Abdominal Radiology, Vol. 42, No. 3, 01.03.2017, p. 870-876.

Research output: Contribution to journalArticle

Ikram, Nabia S. ; Yee, Judy ; Weinstein, Stefanie ; Yeh, Benjamin M. ; Corvera, Carlos U. ; Monto, Alexander ; Hope, Thomas A. / Multiple arterial phase MRI of arterial hypervascular hepatic lesions : improved arterial phase capture and lesion enhancement. In: Abdominal Radiology. 2017 ; Vol. 42, No. 3. pp. 870-876.
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N2 - Purpose: To establish if triple-phase arterial imaging improves the detection of arterial phase hyperintense lesions based on arterial phase capture, motion artifact degradation, and lesion enhancement when compared to single-phase imaging. Materials and methods: Patients at risk for hepatocellular carcinoma were imaged at 3.0T. Seventy-three consecutive patients with a standard single-phase MRI and eighty-five consecutive patients were imaged using extracellular contrast with triple arterial phase MRI using three sequential accelerated acquisitions of 8 s. Arterial phase capture and image quality were qualitatively categorized. Forty single-phase and forty-four triple-phase studies contained arterially enhancing lesions > 1 cm with washout appearance. The contrast-to-noise ratio (CNR) of the lesions was calculated. We compared the differences in means with Student t-tests and those in arterial phase capture with a Chi squared test with Yates correction. Results: The triple-phase acquisitions captured the early or late arterial phases more frequently than did the single-phase acquisition (99% vs 86%; P value = 0.006). Triple-phase also provided greater number of patients with early or late arterial phase imaging without motion artifact (92% vs 79%, P-value = 0.05). The lesion analysis revealed increased maximum CNR in the triple-phase imaging (704.4) vs. single-phase imaging (517.2), P-value < 0.001. Conclusion: Triple-phase acquisition provides more robust arterial phase imaging for hepatic lesions, with increased lesion CNR, compared to standard single-phase arterial phase imaging.

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