Multimodal therapy in perioperative analgesia

Research output: Contribution to journalArticle

Abstract

This article reviews the current evidence for multimodal analgesic options for common surgical procedures. As perioperative physicians, we have come a long way from using only opioids for postoperative pain to combinations of acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), selective Cyclo-oxygenase (COX-2) inhibitors, local anesthetics, N-methyl-d-aspartate (NMDA) receptor antagonists, and regional anesthetics. As discussed in this article, many of these agents have decreased narcotic requirements, improved patient satisfaction, and decreased postanesthesia care unit (PACU) times, as well as morbidity in the perioperative period.

Original languageEnglish (US)
Pages (from-to)59-79
Number of pages21
JournalBest Practice and Research: Clinical Anaesthesiology
Volume28
Issue number1
DOIs
StatePublished - Mar 1 2014

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Perioperative Period
Cyclooxygenase 2 Inhibitors
Narcotics
Prostaglandin-Endoperoxide Synthases
Acetaminophen
Postoperative Pain
Local Anesthetics
Patient Satisfaction
Analgesia
Opioid Analgesics
Analgesics
Anesthetics
Anti-Inflammatory Agents
Morbidity
Physicians
Pharmaceutical Preparations
Therapeutics
aspartic acid receptor

Keywords

  • acute pain
  • adjuvant medication
  • balanced anesthesia
  • chronic postoperative pain
  • multimodal perioperative analgesia
  • persistent postoperative pain
  • postoperative pain
  • regional anesthesia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Multimodal therapy in perioperative analgesia. / Gritsenko, Karina.

In: Best Practice and Research: Clinical Anaesthesiology, Vol. 28, No. 1, 01.03.2014, p. 59-79.

Research output: Contribution to journalArticle

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