Multicopper oxidases in saccharomyces cerevisiae and human pathogenic fungi

Tanmoy Chakraborty, Renáta Tóth, Joshua D. Nosanchuk, Attila Gácser

Research output: Contribution to journalReview article

Abstract

Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summarize our current understanding regarding the functions of MCOs present in Saccharomyces cerevisiae and in different human fungal pathogens. Of the two main MCO groups, the first group of MCOs is involved in iron homoeostasis and the second includes laccases. This review will also discuss their role in the pathogenesis of human fungal pathogens.

Original languageEnglish (US)
Article number56
JournalJournal of Fungi
Volume6
Issue number2
DOIs
StatePublished - Jun 2020

Keywords

  • Iron uptake
  • Laccase
  • Multicopper oxidases
  • Pathogenic fungi
  • Virulence

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Plant Science
  • Microbiology (medical)

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