mRNA and cytoskeletal filaments

Gary Bassell; Robert H. Singer

doi:10.1016/S0955-0674(97)80159-7

mRNA and cytoskeletal filaments

Gary Bassell, Robert H. Singer

Cell Biology

Research output: Contribution to journal › Article › peer-review

203 Scopus citations

Abstract

The localization of some mRNAs to distinct intracellular regions is achieved through interactions of the mRNA with cytoskeletal filaments. RNA-cytoskeletal interactions exist that influence the transport, anchoring and translation of mRNA. Recent analysis of RNA movements in living cells suggests the formation of RNA granules and their active transport along microtubules. The anchoring and translation of mRNA may be mediated by interactions with orthogonal networks of F-actin and elongation factor 1α.

Original language	English (US)
Pages (from-to)	109-115
Number of pages	7
Journal	Current Opinion in Cell Biology
Volume	9
Issue number	1
DOIs	https://doi.org/10.1016/S0955-0674(97)80159-7
State	Published - 1997

ASJC Scopus subject areas

Cell Biology

Access to Document

10.1016/S0955-0674(97)80159-7

Cite this

@article{f466b42a848d4ba59035291bd8918b91,

title = "mRNA and cytoskeletal filaments",

abstract = "The localization of some mRNAs to distinct intracellular regions is achieved through interactions of the mRNA with cytoskeletal filaments. RNA-cytoskeletal interactions exist that influence the transport, anchoring and translation of mRNA. Recent analysis of RNA movements in living cells suggests the formation of RNA granules and their active transport along microtubules. The anchoring and translation of mRNA may be mediated by interactions with orthogonal networks of F-actin and elongation factor 1α.",

author = "Gary Bassell and Singer, {Robert H.}",

note = "Funding Information: We thank Ken Kosik for providing data included in this review. We thank Ken Kosik and John Condeelis for helpful discussions. We also thank the members of RH Singer{\textquoteright}s laboratory for their work and critical input. RH Singer is supported by NIH (National Institutes of Health) grants GM54887 and AR41480, and G Bassell is supported by a Basal O{\textquoteright}Connor award, the March of Dimes.",

year = "1997",

doi = "10.1016/S0955-0674(97)80159-7",

language = "English (US)",

volume = "9",

pages = "109--115",

journal = "Current Opinion in Cell Biology",

issn = "0955-0674",

publisher = "Elsevier Limited",

number = "1",

}

TY - JOUR

T1 - mRNA and cytoskeletal filaments

AU - Bassell, Gary

AU - Singer, Robert H.

N1 - Funding Information: We thank Ken Kosik for providing data included in this review. We thank Ken Kosik and John Condeelis for helpful discussions. We also thank the members of RH Singer’s laboratory for their work and critical input. RH Singer is supported by NIH (National Institutes of Health) grants GM54887 and AR41480, and G Bassell is supported by a Basal O’Connor award, the March of Dimes.

PY - 1997

Y1 - 1997

N2 - The localization of some mRNAs to distinct intracellular regions is achieved through interactions of the mRNA with cytoskeletal filaments. RNA-cytoskeletal interactions exist that influence the transport, anchoring and translation of mRNA. Recent analysis of RNA movements in living cells suggests the formation of RNA granules and their active transport along microtubules. The anchoring and translation of mRNA may be mediated by interactions with orthogonal networks of F-actin and elongation factor 1α.

AB - The localization of some mRNAs to distinct intracellular regions is achieved through interactions of the mRNA with cytoskeletal filaments. RNA-cytoskeletal interactions exist that influence the transport, anchoring and translation of mRNA. Recent analysis of RNA movements in living cells suggests the formation of RNA granules and their active transport along microtubules. The anchoring and translation of mRNA may be mediated by interactions with orthogonal networks of F-actin and elongation factor 1α.

UR - http://www.scopus.com/inward/record.url?scp=0031052636&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031052636&partnerID=8YFLogxK

U2 - 10.1016/S0955-0674(97)80159-7

DO - 10.1016/S0955-0674(97)80159-7

M3 - Article

C2 - 9013679

AN - SCOPUS:0031052636

SN - 0955-0674

VL - 9

SP - 109

EP - 115

JO - Current Opinion in Cell Biology

JF - Current Opinion in Cell Biology

IS - 1

ER -

mRNA and cytoskeletal filaments

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this