mRNA and cytoskeletal filaments

Gary Bassell, Robert H. Singer

Research output: Contribution to journalArticle

195 Citations (Scopus)

Abstract

The localization of some mRNAs to distinct intracellular regions is achieved through interactions of the mRNA with cytoskeletal filaments. RNA-cytoskeletal interactions exist that influence the transport, anchoring and translation of mRNA. Recent analysis of RNA movements in living cells suggests the formation of RNA granules and their active transport along microtubules. The anchoring and translation of mRNA may be mediated by interactions with orthogonal networks of F-actin and elongation factor 1α.

Original languageEnglish (US)
Pages (from-to)109-115
Number of pages7
JournalCurrent Opinion in Cell Biology
Volume9
Issue number1
DOIs
StatePublished - 1997

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Cytoskeleton
Protein Biosynthesis
RNA
Messenger RNA
Peptide Elongation Factor 1
Active Biological Transport
Microtubules
Actins

ASJC Scopus subject areas

  • Cell Biology

Cite this

mRNA and cytoskeletal filaments. / Bassell, Gary; Singer, Robert H.

In: Current Opinion in Cell Biology, Vol. 9, No. 1, 1997, p. 109-115.

Research output: Contribution to journalArticle

Bassell, Gary ; Singer, Robert H. / mRNA and cytoskeletal filaments. In: Current Opinion in Cell Biology. 1997 ; Vol. 9, No. 1. pp. 109-115.
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