TY - JOUR
T1 - MRI Presentation of Infectious Intracranial Aneurysms in Infective Endocarditis
AU - Migdady, Ibrahim
AU - Rice, Cory J.
AU - Hassett, Catherine
AU - Zhang, Lucy Q.
AU - Wisco, Dolora
AU - Uchino, Ken
AU - Cho, Sung Min
N1 - Publisher Copyright:
© 2018, Springer Science+Business Media, LLC, part of Springer Nature and Neurocritical Care Society.
PY - 2019/6/15
Y1 - 2019/6/15
N2 - Background: The radiographic appearance of infectious intracranial aneurysms (IIAs) of infective endocarditis (IE) on magnetic resonance imaging (MRI) of brain is varied. We aimed to describe the IIA-specific MRI features in a series of patients with IIAs. Methods: Records of patients with active IE who had digital subtraction angiography (DSA) at a tertiary medical center from January 2011 to December 2016 were reviewed. MRIs performed prior to IIA treatment were reviewed for findings on susceptibility-weighted imaging (SWI), diffusion-weighted imaging, and T1 with and without contrast. Results: Of the 732 patients with IE, 53 (7%) had IIAs. Of these, 28 patients had an evaluable pre-treatment MRI, in whom 33 IIAs were imaged. MRI to DSA median time was 1 day (interquartile range = 1–5). On MRI, 12 (36%) IIAs had SWI lesion with contrast enhancement, 7 (21%) had cerebral microbleeds, 3 (11%) had sulcal SWI lesion, 2 (6%) IIAs had abscesses, 3 (9%) had intraparenchymal hemorrhage, 3 (9%) had subarachnoid hemorrhage, and 6 (18%) had ischemic stroke at the anatomical locations of IIAs. Four IIAs (12%) had no correlating MRI findings, though those patients had MRI without contrast. Conclusion: The MRI features such as SWI lesion and contrast enhancement were the commonest MRI presentations associated with the presence of IIA.
AB - Background: The radiographic appearance of infectious intracranial aneurysms (IIAs) of infective endocarditis (IE) on magnetic resonance imaging (MRI) of brain is varied. We aimed to describe the IIA-specific MRI features in a series of patients with IIAs. Methods: Records of patients with active IE who had digital subtraction angiography (DSA) at a tertiary medical center from January 2011 to December 2016 were reviewed. MRIs performed prior to IIA treatment were reviewed for findings on susceptibility-weighted imaging (SWI), diffusion-weighted imaging, and T1 with and without contrast. Results: Of the 732 patients with IE, 53 (7%) had IIAs. Of these, 28 patients had an evaluable pre-treatment MRI, in whom 33 IIAs were imaged. MRI to DSA median time was 1 day (interquartile range = 1–5). On MRI, 12 (36%) IIAs had SWI lesion with contrast enhancement, 7 (21%) had cerebral microbleeds, 3 (11%) had sulcal SWI lesion, 2 (6%) IIAs had abscesses, 3 (9%) had intraparenchymal hemorrhage, 3 (9%) had subarachnoid hemorrhage, and 6 (18%) had ischemic stroke at the anatomical locations of IIAs. Four IIAs (12%) had no correlating MRI findings, though those patients had MRI without contrast. Conclusion: The MRI features such as SWI lesion and contrast enhancement were the commonest MRI presentations associated with the presence of IIA.
KW - Cerebral angiography
KW - Infectious intracranial aneurysms
KW - Infective endocarditis
KW - MRI
UR - http://www.scopus.com/inward/record.url?scp=85057968279&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85057968279&partnerID=8YFLogxK
U2 - 10.1007/s12028-018-0654-1
DO - 10.1007/s12028-018-0654-1
M3 - Article
C2 - 30519794
AN - SCOPUS:85057968279
SN - 1541-6933
VL - 30
SP - 658
EP - 665
JO - Neurocritical Care
JF - Neurocritical Care
IS - 3
ER -