MR cholangiography in children and young adults with biliary disease

Karen I. Norton, Ronald B J Glass, Debora Kogan-Liberman, Sukru Emre, Myron Schwartz, Benjamin L. Shneider

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

OBJECTIVE. Our objective was to describe the MR cholangiography findings for young patients with suspected biliary disease who underwent half-Fourier acquisition fast Spin-echo technique with respiratory triggering. SUBJECTS AND METHODS. Twenty-eight MR cholangiography studies were performed in 22 patients on a 1.5-T MR unit. Ten of these 22 patients had undergone liver transplantation. RESULTS. MR cholangiography revealed abnormalities of both the extrahepatic and the intrahepatic major and minor bile duct systems, despite the small diameter of the duct system in this group of patients. Four patterns of biliary disease were shown: global dilatation of extrahepatic or intrahepatic ducts (n = 7); segmental, uniform dilatation of central or peripheral intrahepatic ducts (n = 9); segmental, nonuniform dilatation of central or peripheral intrahepatic ducts (n = 2); and fusiform ectasia with segmental, irregular intrahepatic dilatation and bile lakes (n = 2). The findings of eight studies were interpreted as normal. The four patterns of abnormalities were correlated with the results from percutaneous transhepatic cholangiography, T-tube cholangiography, and liver biopsy and with clinical and surgical information, as available. CONCLUSION. MR cholangiography is a noninvasive technique for evaluation of biliary disease. The improved resolution afforded by respiratory triggering permits evaluation of both major and minor bile ducts, even in young, uncooperative subjects. Four patterns of abnormalities were prospectively identified, correlated with other information, and used to direct clinical treatment.

Original languageEnglish (US)
Pages (from-to)1239-1244
Number of pages6
JournalAmerican Journal of Roentgenology
Volume172
Issue number5
StatePublished - May 1999
Externally publishedYes

Fingerprint

Cholangiography
Young Adult
Dilatation
Bile Ducts
Pathologic Dilatations
Lakes
Bile
Liver Transplantation
Biopsy
Liver

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Norton, K. I., Glass, R. B. J., Kogan-Liberman, D., Emre, S., Schwartz, M., & Shneider, B. L. (1999). MR cholangiography in children and young adults with biliary disease. American Journal of Roentgenology, 172(5), 1239-1244.

MR cholangiography in children and young adults with biliary disease. / Norton, Karen I.; Glass, Ronald B J; Kogan-Liberman, Debora; Emre, Sukru; Schwartz, Myron; Shneider, Benjamin L.

In: American Journal of Roentgenology, Vol. 172, No. 5, 05.1999, p. 1239-1244.

Research output: Contribution to journalArticle

Norton, KI, Glass, RBJ, Kogan-Liberman, D, Emre, S, Schwartz, M & Shneider, BL 1999, 'MR cholangiography in children and young adults with biliary disease', American Journal of Roentgenology, vol. 172, no. 5, pp. 1239-1244.
Norton KI, Glass RBJ, Kogan-Liberman D, Emre S, Schwartz M, Shneider BL. MR cholangiography in children and young adults with biliary disease. American Journal of Roentgenology. 1999 May;172(5):1239-1244.
Norton, Karen I. ; Glass, Ronald B J ; Kogan-Liberman, Debora ; Emre, Sukru ; Schwartz, Myron ; Shneider, Benjamin L. / MR cholangiography in children and young adults with biliary disease. In: American Journal of Roentgenology. 1999 ; Vol. 172, No. 5. pp. 1239-1244.
@article{9cc1dc2459b7405ab6d87edf76b5f403,
title = "MR cholangiography in children and young adults with biliary disease",
abstract = "OBJECTIVE. Our objective was to describe the MR cholangiography findings for young patients with suspected biliary disease who underwent half-Fourier acquisition fast Spin-echo technique with respiratory triggering. SUBJECTS AND METHODS. Twenty-eight MR cholangiography studies were performed in 22 patients on a 1.5-T MR unit. Ten of these 22 patients had undergone liver transplantation. RESULTS. MR cholangiography revealed abnormalities of both the extrahepatic and the intrahepatic major and minor bile duct systems, despite the small diameter of the duct system in this group of patients. Four patterns of biliary disease were shown: global dilatation of extrahepatic or intrahepatic ducts (n = 7); segmental, uniform dilatation of central or peripheral intrahepatic ducts (n = 9); segmental, nonuniform dilatation of central or peripheral intrahepatic ducts (n = 2); and fusiform ectasia with segmental, irregular intrahepatic dilatation and bile lakes (n = 2). The findings of eight studies were interpreted as normal. The four patterns of abnormalities were correlated with the results from percutaneous transhepatic cholangiography, T-tube cholangiography, and liver biopsy and with clinical and surgical information, as available. CONCLUSION. MR cholangiography is a noninvasive technique for evaluation of biliary disease. The improved resolution afforded by respiratory triggering permits evaluation of both major and minor bile ducts, even in young, uncooperative subjects. Four patterns of abnormalities were prospectively identified, correlated with other information, and used to direct clinical treatment.",
author = "Norton, {Karen I.} and Glass, {Ronald B J} and Debora Kogan-Liberman and Sukru Emre and Myron Schwartz and Shneider, {Benjamin L.}",
year = "1999",
month = "5",
language = "English (US)",
volume = "172",
pages = "1239--1244",
journal = "American Journal of Roentgenology",
issn = "0361-803X",
publisher = "American Roentgen Ray Society",
number = "5",

}

TY - JOUR

T1 - MR cholangiography in children and young adults with biliary disease

AU - Norton, Karen I.

AU - Glass, Ronald B J

AU - Kogan-Liberman, Debora

AU - Emre, Sukru

AU - Schwartz, Myron

AU - Shneider, Benjamin L.

PY - 1999/5

Y1 - 1999/5

N2 - OBJECTIVE. Our objective was to describe the MR cholangiography findings for young patients with suspected biliary disease who underwent half-Fourier acquisition fast Spin-echo technique with respiratory triggering. SUBJECTS AND METHODS. Twenty-eight MR cholangiography studies were performed in 22 patients on a 1.5-T MR unit. Ten of these 22 patients had undergone liver transplantation. RESULTS. MR cholangiography revealed abnormalities of both the extrahepatic and the intrahepatic major and minor bile duct systems, despite the small diameter of the duct system in this group of patients. Four patterns of biliary disease were shown: global dilatation of extrahepatic or intrahepatic ducts (n = 7); segmental, uniform dilatation of central or peripheral intrahepatic ducts (n = 9); segmental, nonuniform dilatation of central or peripheral intrahepatic ducts (n = 2); and fusiform ectasia with segmental, irregular intrahepatic dilatation and bile lakes (n = 2). The findings of eight studies were interpreted as normal. The four patterns of abnormalities were correlated with the results from percutaneous transhepatic cholangiography, T-tube cholangiography, and liver biopsy and with clinical and surgical information, as available. CONCLUSION. MR cholangiography is a noninvasive technique for evaluation of biliary disease. The improved resolution afforded by respiratory triggering permits evaluation of both major and minor bile ducts, even in young, uncooperative subjects. Four patterns of abnormalities were prospectively identified, correlated with other information, and used to direct clinical treatment.

AB - OBJECTIVE. Our objective was to describe the MR cholangiography findings for young patients with suspected biliary disease who underwent half-Fourier acquisition fast Spin-echo technique with respiratory triggering. SUBJECTS AND METHODS. Twenty-eight MR cholangiography studies were performed in 22 patients on a 1.5-T MR unit. Ten of these 22 patients had undergone liver transplantation. RESULTS. MR cholangiography revealed abnormalities of both the extrahepatic and the intrahepatic major and minor bile duct systems, despite the small diameter of the duct system in this group of patients. Four patterns of biliary disease were shown: global dilatation of extrahepatic or intrahepatic ducts (n = 7); segmental, uniform dilatation of central or peripheral intrahepatic ducts (n = 9); segmental, nonuniform dilatation of central or peripheral intrahepatic ducts (n = 2); and fusiform ectasia with segmental, irregular intrahepatic dilatation and bile lakes (n = 2). The findings of eight studies were interpreted as normal. The four patterns of abnormalities were correlated with the results from percutaneous transhepatic cholangiography, T-tube cholangiography, and liver biopsy and with clinical and surgical information, as available. CONCLUSION. MR cholangiography is a noninvasive technique for evaluation of biliary disease. The improved resolution afforded by respiratory triggering permits evaluation of both major and minor bile ducts, even in young, uncooperative subjects. Four patterns of abnormalities were prospectively identified, correlated with other information, and used to direct clinical treatment.

UR - http://www.scopus.com/inward/record.url?scp=0032707290&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032707290&partnerID=8YFLogxK

M3 - Article

C2 - 10227496

AN - SCOPUS:0032707290

VL - 172

SP - 1239

EP - 1244

JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

SN - 0361-803X

IS - 5

ER -