moxDendra2: an inert photoswitchable protein for oxidizing environments

Andrii Kaberniuk, Nicholas C. Morano, Vladislav Verkhusha, Erik Lee Snapp

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Fluorescent proteins (FPs) that can be optically highlighted enable PALM super-resolution microscopy and pulse-chase experiments of cellular molecules. Most FPs evolved in cytoplasmic environments either in the original source organism or in the cytoplasm of bacteria during the course of optimization for research applications. Consequently, many FPs may fold incorrectly in the chemically distinct environments in subcellular organelles. Here, we describe the first monomeric photoswitchable (from green to bright red) FP adapted for oxidizing environments.

Original languageEnglish (US)
Pages (from-to)2106-2109
Number of pages4
JournalChemical Communications
Volume53
Issue number13
DOIs
StatePublished - 2017

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Proteins
Bacteria
Microscopic examination
Molecules
Experiments
red fluorescent protein

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

moxDendra2 : an inert photoswitchable protein for oxidizing environments. / Kaberniuk, Andrii; Morano, Nicholas C.; Verkhusha, Vladislav; Snapp, Erik Lee.

In: Chemical Communications, Vol. 53, No. 13, 2017, p. 2106-2109.

Research output: Contribution to journalArticle

Kaberniuk, Andrii ; Morano, Nicholas C. ; Verkhusha, Vladislav ; Snapp, Erik Lee. / moxDendra2 : an inert photoswitchable protein for oxidizing environments. In: Chemical Communications. 2017 ; Vol. 53, No. 13. pp. 2106-2109.
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