Mouse models for the study of fungal pneumonia: A collection of detailed experimental protocols for the study of Coccidioides, Cryptococcus, Fusarium, Histoplasma and combined infection due to Aspergillus-Rhizopus

Maged Muhammed, Marta Feldmesser, Lisa F. Shubitz, Michail S. Lionakis, Anita Sil, Yan Wang, Justin Glavis-Blom, Russell E. Lewis, John Galgiani, Arturo Casadevall, Dimitrios P. Kontoyiannis, Eleftherios Mylonakis

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Mouse models have facilitated the study of fungal pneumonia. In this report, we present the working protocols of groups that are working on the following pathogens: Aspergillus, Coccidioides, Cryptococcus, Fusarium, Histoplasma and Rhizopus. We describe the experimental procedures and the detailed methods that have been followed in the experienced laboratories to study pulmonary fungal infection; we also discuss the anticipated results and technical notes, and provide the practical advices that will help the users of these models.

Original languageEnglish (US)
Number of pages1
Issue number3
Publication statusPublished - Jan 1 2012


ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Microbiology (medical)
  • Infectious Diseases

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