Mouse models for the study of fungal pneumonia: a collection of detailed experimental protocols for the study of Coccidioides, Cryptococcus, Fusarium, Histoplasma and combined infection due to Aspergillus-Rhizopus.

Maged Muhammed, Marta Feldmesser, Lisa F. Shubitz, Michail S. Lionakis, Anita Sil, Yan Wang, Justin Glavis-Bloom, Russell E. Lewis, John N. Galgiani, Arturo Casadevall, Dimitrios P. Kontoyiannis, Eleftherios Mylonakis

Research output: Contribution to journalArticle

Abstract

Mouse models have facilitated the study of fungal pneumonia. In this report, we present the working protocols of groups that are working on the following pathogens: Aspergillus, Coccidioides, Cryptococcus, Fusarium, Histoplasma and Rhizopus. We describe the experimental procedures and the detailed methods that have been followed in the experienced laboratories to study pulmonary fungal infection; we also discuss the anticipated results and technical notes, and provide the practical advices that will help the users of these models.

Original languageEnglish (US)
Pages (from-to)329-338
Number of pages10
JournalVirulence
Volume3
Issue number3
Publication statusPublished - May 1 2012
Externally publishedYes

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ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology
  • Parasitology
  • Immunology
  • Microbiology (medical)

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