Morphologic Differences of the Endocardial Electrogram in Beats of Sinus and Ventricular Origin

GORDON F. TOMASELLI, ANTON P. NIELSEN, WILBUR L. FINKE, LINA SINGUPTA, JOHN G. CLARK, JERRY G. GRIFFIN

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

The lack of accurate arrhythmia detection and identification is one of the major obstacles to improvement in the efficacy of antitachycardia devices. We evaluated a method for detection of beats of ventricular origin compared to sinus rhythm based on the morphology of the endocardial electrogram. In order to compare mechanically induced ventricular beats to normal sinus beats, endocardial electrograms from a standard pacing electrode were recorded from eight open‐chested dogs. Time and frequency domain features analyzed included peak‐to‐peak amplitude (AMP), maximal slew rate (dV/dT). and frequency content (‐3 dB downpoint). Quantitative morphologic comparison of the waveforms was performed using standard correlation and by the absolute area of difference between the waveform and a sinus beat template. The AMP and dV/dT for a group of ventricular beats did not differ significantly from beats of sinus origin. In the unipolar configurution ‐3 dB for ventricular beats was significantly different from sinus beats (p = .01), but overlap occurred in three of eight cases. Conversely, using either method of assessment of morphological differences, all ventricular beats could be identified without overlapping the values for normal beats. We concluded that morphologic analysis of the endocardial electrogram by such methods may be a highly accurate means of distinguishing between beats of sinus and ventricular origins. This technique may also be applicable to the problem of automatic rhythm identification by implanted devices.

Original languageEnglish (US)
Pages (from-to)254-262
Number of pages9
JournalPacing and Clinical Electrophysiology
Volume11
Issue number3
DOIs
StatePublished - Mar 1988
Externally publishedYes

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Keywords

  • antitachycardia devices
  • endocardial electrogram morphology
  • implanted defibriliator
  • pacemakers
  • tachycardia recognition

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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