Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome

Herbert H. Schaumburg; Robert Byck; Robert Gerstl; Jan H. Mashman

doi:10.1126/science.163.3869.826

Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome

Herbert H. Schaumburg, Robert Byck, Robert Gerstl, Jan H. Mashman

Neurology

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193 Scopus citations

Abstract

Monosodium L-glutamate is the cause of the Chinese restaurant syndrome and can precipitate headaches. In appropriate doses it causes burning sensations, facial pressure, and chest pain. These are pharmacological effects obeying a dose-effect relationship. There is considerable variation in oral threshold doses among individuals.

Original language	English (US)
Pages (from-to)	826-828
Number of pages	3
Journal	Science
Volume	163
Issue number	3869
DOIs	https://doi.org/10.1126/science.163.3869.826
State	Published - Jan 1 1969

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Schaumburg, H. H., Byck, R., Gerstl, R., & Mashman, J. H. (1969). Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome. Science, 163(3869), 826-828. https://doi.org/10.1126/science.163.3869.826

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Access to Document

10.1126/science.163.3869.826