Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome

Herbert H. Schaumburg, Robert Byck, Robert Gerstl, Jan H. Mashman

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195 Scopus citations

Abstract

Monosodium L-glutamate is the cause of the Chinese restaurant syndrome and can precipitate headaches. In appropriate doses it causes burning sensations, facial pressure, and chest pain. These are pharmacological effects obeying a dose-effect relationship. There is considerable variation in oral threshold doses among individuals.

Original languageEnglish (US)
Pages (from-to)826-828
Number of pages3
JournalScience
Volume163
Issue number3869
DOIs
StatePublished - Jan 1 1969

ASJC Scopus subject areas

  • General

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    Schaumburg, H. H., Byck, R., Gerstl, R., & Mashman, J. H. (1969). Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome. Science, 163(3869), 826-828. https://doi.org/10.1126/science.163.3869.826