Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome

Herbert H. Schaumburg, Robert Byck, Robert Gerstl, Jan H. Mashman

Research output: Contribution to journalArticle

189 Citations (Scopus)

Abstract

Monosodium L-glutamate is the cause of the Chinese restaurant syndrome and can precipitate headaches. In appropriate doses it causes burning sensations, facial pressure, and chest pain. These are pharmacological effects obeying a dose-effect relationship. There is considerable variation in oral threshold doses among individuals.

Original languageEnglish (US)
Pages (from-to)826-828
Number of pages3
JournalScience
Volume163
Issue number3869
StatePublished - 1969

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Sodium Glutamate
Facial Pain
Chest Pain
Headache
Glutamic Acid
Pharmacology
Pressure
Glutamate Monosodium Sensitivity

ASJC Scopus subject areas

  • General

Cite this

Schaumburg, H. H., Byck, R., Gerstl, R., & Mashman, J. H. (1969). Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome. Science, 163(3869), 826-828.

Monosodium L-glutamate : Its pharmacology and role in the Chinese restaurant syndrome. / Schaumburg, Herbert H.; Byck, Robert; Gerstl, Robert; Mashman, Jan H.

In: Science, Vol. 163, No. 3869, 1969, p. 826-828.

Research output: Contribution to journalArticle

Schaumburg, HH, Byck, R, Gerstl, R & Mashman, JH 1969, 'Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome', Science, vol. 163, no. 3869, pp. 826-828.
Schaumburg HH, Byck R, Gerstl R, Mashman JH. Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome. Science. 1969;163(3869):826-828.
Schaumburg, Herbert H. ; Byck, Robert ; Gerstl, Robert ; Mashman, Jan H. / Monosodium L-glutamate : Its pharmacology and role in the Chinese restaurant syndrome. In: Science. 1969 ; Vol. 163, No. 3869. pp. 826-828.
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