Monoclonal gammopathies in the West of Ireland: A preliminary study

John M. Greally, Gerard O'Toole, Hugh McCann, Helen Grimes, Brian O'Connor, Gerard Solan, Niall Walsh, Ernest Egan

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Abstract

A STUDY was carried out, based on laboratory test records of patients attending hospital, into the incidence of monoclonal gammopathy in the West of Ireland. Two hundred and ninety-six fully verified cases occurred in a seven and a half year period, giving an incidence for the study of 9.2 cases per population per annum. A diagnosis of malignancy was confirmed on 126 cases from the Western Health Board part of Connacht, either multiple myeloma (117 cases, or 47.4% of W.H.B. monoclonal gammo-pathies) or Waldenström's Macroglo-bulinaemia (9, 3.6%). The incidence of multiple myeloma was found to be 4.5 cases per 100,000 cases per annum. No diagnosis was obtained on many of the remaining 170 cases. A notable feature was the concentration of monoclonal gammopathy and multiple myeloma in certain areas. The basis for this variation is discussed.

Original languageEnglish (US)
Pages (from-to)94-101
Number of pages8
JournalIrish Journal of Medical Science
Volume154
Issue number3
DOIs
StatePublished - Mar 1 1985
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Greally, J. M., O'Toole, G., McCann, H., Grimes, H., O'Connor, B., Solan, G., Walsh, N., & Egan, E. (1985). Monoclonal gammopathies in the West of Ireland: A preliminary study. Irish Journal of Medical Science, 154(3), 94-101. https://doi.org/10.1007/BF02937224