Molecular genetics of head and neck cancer (Review)

Shitij Arora, Prachi Aggarwal, Amit Pathak, Rekha Bhandari, Frantz Duffoo, Subhash C. Gulati

Research output: Contribution to journalReview article

10 Scopus citations

Abstract

Understanding of molecular regulatory pathways presents a novel therapeutic approach for the treatment of head and neck cancer. These specific check points are becoming the targeted therapeutic approach. In this review, we highlight certain major signaling mechanisms, which are involved in the pathophysiology of head and neck cancer. Also, we discuss the current ongoing trials based on the in vitro success of targeted therapies.

Original languageEnglish (US)
Pages (from-to)19-22
Number of pages4
JournalMolecular Medicine Reports
Volume6
Issue number1
DOIs
Publication statusPublished - Jul 1 2012
Externally publishedYes

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Keywords

  • Head and neck cancer
  • Regulatory pathways

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Oncology
  • Cancer Research

Cite this

Arora, S., Aggarwal, P., Pathak, A., Bhandari, R., Duffoo, F., & Gulati, S. C. (2012). Molecular genetics of head and neck cancer (Review). Molecular Medicine Reports, 6(1), 19-22. https://doi.org/10.3892/mmr.2012.889