Molecular diagnostics in the neoplasms of the pancreas, liver, gall bladder, and extrahepatic biliary tract

Michael Weindel; Muhammad Zulfiqar; Amarpreet Bhalla; Vinod B. Shidham

doi:10.1016/j.cll.2013.08.002

Molecular diagnostics in the neoplasms of the pancreas, liver, gall bladder, and extrahepatic biliary tract

Michael Weindel, Muhammad Zulfiqar, Amarpreet Bhalla, Vinod B. Shidham

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Pancreatic neoplasms, including ductal adenocarcinoma, intraductal papillary mucinous neoplasm, solid pseudopapillary neoplasm, pancreatic endocrine neoplasms, acinar cell carcinoma, and ampullary carcinoma, are associated with different genetic abnormalities. Liver neoplasms, including hepatic adenomas, hepatocellular carcinomas, and cholangiocarcinomas, are associated with identifiable risk factors and genetic changes. Gall bladder adenomas and adenocarcinomas arise from distinct molecular pathways. The molecular abnormalities seen in these tumors are not used routinely in the molecular diagnostic laboratory.

Original language	English (US)
Pages (from-to)	875-880
Number of pages	6
Journal	Clinics in Laboratory Medicine
Volume	33
Issue number	4
DOIs	https://doi.org/10.1016/j.cll.2013.08.002
State	Published - Dec 2013
Externally published	Yes

Keywords

Extrahepatic biliary tract
Gall bladder adenocarcinoma
Gall bladder adenoma
Liver neoplasms
Molecular diagnostics
Pancreatic neoplasms

ASJC Scopus subject areas

Clinical Biochemistry
Biochemistry, medical

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10.1016/j.cll.2013.08.002

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title = "Molecular diagnostics in the neoplasms of the pancreas, liver, gall bladder, and extrahepatic biliary tract",

abstract = "Pancreatic neoplasms, including ductal adenocarcinoma, intraductal papillary mucinous neoplasm, solid pseudopapillary neoplasm, pancreatic endocrine neoplasms, acinar cell carcinoma, and ampullary carcinoma, are associated with different genetic abnormalities. Liver neoplasms, including hepatic adenomas, hepatocellular carcinomas, and cholangiocarcinomas, are associated with identifiable risk factors and genetic changes. Gall bladder adenomas and adenocarcinomas arise from distinct molecular pathways. The molecular abnormalities seen in these tumors are not used routinely in the molecular diagnostic laboratory.",

keywords = "Extrahepatic biliary tract, Gall bladder adenocarcinoma, Gall bladder adenoma, Liver neoplasms, Molecular diagnostics, Pancreatic neoplasms",

author = "Michael Weindel and Muhammad Zulfiqar and Amarpreet Bhalla and Shidham, {Vinod B.}",

year = "2013",

month = dec,

doi = "10.1016/j.cll.2013.08.002",

language = "English (US)",

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T1 - Molecular diagnostics in the neoplasms of the pancreas, liver, gall bladder, and extrahepatic biliary tract

AU - Weindel, Michael

AU - Zulfiqar, Muhammad

AU - Bhalla, Amarpreet

AU - Shidham, Vinod B.

PY - 2013/12

Y1 - 2013/12

N2 - Pancreatic neoplasms, including ductal adenocarcinoma, intraductal papillary mucinous neoplasm, solid pseudopapillary neoplasm, pancreatic endocrine neoplasms, acinar cell carcinoma, and ampullary carcinoma, are associated with different genetic abnormalities. Liver neoplasms, including hepatic adenomas, hepatocellular carcinomas, and cholangiocarcinomas, are associated with identifiable risk factors and genetic changes. Gall bladder adenomas and adenocarcinomas arise from distinct molecular pathways. The molecular abnormalities seen in these tumors are not used routinely in the molecular diagnostic laboratory.

AB - Pancreatic neoplasms, including ductal adenocarcinoma, intraductal papillary mucinous neoplasm, solid pseudopapillary neoplasm, pancreatic endocrine neoplasms, acinar cell carcinoma, and ampullary carcinoma, are associated with different genetic abnormalities. Liver neoplasms, including hepatic adenomas, hepatocellular carcinomas, and cholangiocarcinomas, are associated with identifiable risk factors and genetic changes. Gall bladder adenomas and adenocarcinomas arise from distinct molecular pathways. The molecular abnormalities seen in these tumors are not used routinely in the molecular diagnostic laboratory.

KW - Extrahepatic biliary tract

KW - Gall bladder adenocarcinoma

KW - Gall bladder adenoma

KW - Liver neoplasms

KW - Molecular diagnostics

KW - Pancreatic neoplasms

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DO - 10.1016/j.cll.2013.08.002

M3 - Review article

C2 - 24267192

AN - SCOPUS:84888203955

SN - 0272-2712

VL - 33

SP - 875

EP - 880

JO - Clinics in Laboratory Medicine

JF - Clinics in Laboratory Medicine

IS - 4

ER -

Molecular diagnostics in the neoplasms of the pancreas, liver, gall bladder, and extrahepatic biliary tract

Abstract

Keywords

ASJC Scopus subject areas

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