Abstract
Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 861-866 |
| Number of pages | 6 |
| Journal | Clinics in Laboratory Medicine |
| Volume | 33 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 1 2013 |
| Externally published | Yes |
Keywords
- Appendix
- BRAF
- KRAS
- Microsatellite instability
- Small intestine
ASJC Scopus subject areas
- Clinical Biochemistry
- Biochemistry, medical
Cite this
Molecular diagnostics in the neoplasms of small intestine and appendix. / Bhalla, Amarpreet; Zulfiqar, Muhammad; Weindel, Michael; Shidham, Vinod B.
In: Clinics in Laboratory Medicine, Vol. 33, No. 4, 01.12.2013, p. 861-866.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Molecular diagnostics in the neoplasms of small intestine and appendix
AU - Bhalla, Amarpreet
AU - Zulfiqar, Muhammad
AU - Weindel, Michael
AU - Shidham, Vinod B.
PY - 2013/12/1
Y1 - 2013/12/1
N2 - Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.
AB - Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.
KW - Appendix
KW - BRAF
KW - KRAS
KW - Microsatellite instability
KW - Small intestine
UR - http://www.scopus.com/inward/record.url?scp=84888204840&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84888204840&partnerID=8YFLogxK
U2 - 10.1016/j.cll.2013.08.007
DO - 10.1016/j.cll.2013.08.007
M3 - Review article
C2 - 24267190
AN - SCOPUS:84888204840
VL - 33
SP - 861
EP - 866
JO - Clinics in Laboratory Medicine
JF - Clinics in Laboratory Medicine
SN - 0272-2712
IS - 4
ER -