Molecular diagnostics in the neoplasms of small intestine and appendix

Amarpreet Bhalla, Muhammad Zulfiqar, Michael Weindel, Vinod B. Shidham

Research output: Contribution to journalReview article

Abstract

Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.

Original languageEnglish (US)
Pages (from-to)861-866
Number of pages6
JournalClinics in Laboratory Medicine
Volume33
Issue number4
DOIs
StatePublished - Dec 1 2013
Externally publishedYes

Keywords

  • Appendix
  • BRAF
  • KRAS
  • Microsatellite instability
  • Small intestine

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

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