Molecular diagnostics in the neoplasms of small intestine and appendix

Amarpreet Bhalla; Muhammad Zulfiqar; Michael Weindel; Vinod B. Shidham

doi:10.1016/j.cll.2013.08.007

Molecular diagnostics in the neoplasms of small intestine and appendix

Amarpreet Bhalla, Muhammad Zulfiqar, Michael Weindel, Vinod B. Shidham

Research output: Contribution to journal › Review article › peer-review

Abstract

Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.

Original language	English (US)
Pages (from-to)	861-866
Number of pages	6
Journal	Clinics in Laboratory Medicine
Volume	33
Issue number	4
DOIs	https://doi.org/10.1016/j.cll.2013.08.007
State	Published - Dec 1 2013
Externally published	Yes

Keywords

Appendix
BRAF
KRAS
Microsatellite instability
Small intestine

ASJC Scopus subject areas

Clinical Biochemistry
Biochemistry, medical

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title = "Molecular diagnostics in the neoplasms of small intestine and appendix",

abstract = "Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.",

keywords = "Appendix, BRAF, KRAS, Microsatellite instability, Small intestine",

author = "Amarpreet Bhalla and Muhammad Zulfiqar and Michael Weindel and Shidham, {Vinod B.}",

year = "2013",

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day = "1",

doi = "10.1016/j.cll.2013.08.007",

language = "English (US)",

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pages = "861--866",

journal = "Clinics in Laboratory Medicine",

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TY - JOUR

T1 - Molecular diagnostics in the neoplasms of small intestine and appendix

AU - Bhalla, Amarpreet

AU - Zulfiqar, Muhammad

AU - Weindel, Michael

AU - Shidham, Vinod B.

PY - 2013/12/1

Y1 - 2013/12/1

N2 - Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.

AB - Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.

KW - Appendix

KW - BRAF

KW - KRAS

KW - Microsatellite instability

KW - Small intestine

UR - http://www.scopus.com/inward/record.url?scp=84888204840&partnerID=8YFLogxK

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U2 - 10.1016/j.cll.2013.08.007

DO - 10.1016/j.cll.2013.08.007

M3 - Review article

C2 - 24267190

AN - SCOPUS:84888204840

VL - 33

SP - 861

EP - 866

JO - Clinics in Laboratory Medicine

JF - Clinics in Laboratory Medicine

SN - 0272-2712

IS - 4

ER -