Molecular diagnostics in the neoplasms of small intestine and appendix

Amarpreet Bhalla, Muhammad Zulfiqar, Michael Weindel, Vinod B. Shidham

Research output: Contribution to journalReview article

Abstract

Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.

Original languageEnglish (US)
Pages (from-to)861-866
Number of pages6
JournalClinics in Laboratory Medicine
Volume33
Issue number4
DOIs
StatePublished - Dec 1 2013
Externally publishedYes

Keywords

  • Appendix
  • BRAF
  • KRAS
  • Microsatellite instability
  • Small intestine

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

Molecular diagnostics in the neoplasms of small intestine and appendix. / Bhalla, Amarpreet; Zulfiqar, Muhammad; Weindel, Michael; Shidham, Vinod B.

In: Clinics in Laboratory Medicine, Vol. 33, No. 4, 01.12.2013, p. 861-866.

Research output: Contribution to journalReview article

Bhalla, Amarpreet ; Zulfiqar, Muhammad ; Weindel, Michael ; Shidham, Vinod B. / Molecular diagnostics in the neoplasms of small intestine and appendix. In: Clinics in Laboratory Medicine. 2013 ; Vol. 33, No. 4. pp. 861-866.
@article{292e0c2ffec44d27be95cd20497e6966,
title = "Molecular diagnostics in the neoplasms of small intestine and appendix",
abstract = "Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.",
keywords = "Appendix, BRAF, KRAS, Microsatellite instability, Small intestine",
author = "Amarpreet Bhalla and Muhammad Zulfiqar and Michael Weindel and Shidham, {Vinod B.}",
year = "2013",
month = "12",
day = "1",
doi = "10.1016/j.cll.2013.08.007",
language = "English (US)",
volume = "33",
pages = "861--866",
journal = "Clinics in Laboratory Medicine",
issn = "0272-2712",
publisher = "W.B. Saunders Ltd",
number = "4",

}

TY - JOUR

T1 - Molecular diagnostics in the neoplasms of small intestine and appendix

AU - Bhalla, Amarpreet

AU - Zulfiqar, Muhammad

AU - Weindel, Michael

AU - Shidham, Vinod B.

PY - 2013/12/1

Y1 - 2013/12/1

N2 - Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.

AB - Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.

KW - Appendix

KW - BRAF

KW - KRAS

KW - Microsatellite instability

KW - Small intestine

UR - http://www.scopus.com/inward/record.url?scp=84888204840&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84888204840&partnerID=8YFLogxK

U2 - 10.1016/j.cll.2013.08.007

DO - 10.1016/j.cll.2013.08.007

M3 - Review article

C2 - 24267190

AN - SCOPUS:84888204840

VL - 33

SP - 861

EP - 866

JO - Clinics in Laboratory Medicine

JF - Clinics in Laboratory Medicine

SN - 0272-2712

IS - 4

ER -