Modulations in the oscillatory activity of the Globus Pallidus internus neurons during a behavioral task-A point process analysis

Shreya Saxena, John T. Gale, Emad N. Eskandar, Sridevi V. Sarma

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

The behavioral state of a subject is hypothesized to be reflected in the oscillatory modulations of the spiking activity of certain groups of neurons. In particular, the beta- and gamma-bands have been experimentally shown to be related to movement in the motor cortex and parts of the basal ganglia. Here, we analyze the relationship between directional tuning and oscillations in the beta- and gamma-bands of the neurons in the Globus Pallidus internus (GPi) of two healthy nonhuman primates during a radial center-out motor task. We find that, during the planning stages of the movement, the percentage of directionally tuned neurons displaying gamma oscillations increases when compared to the percentage of directionally tuned neurons displaying beta oscillations. A similar trend is not seen in non-directionally tuned neurons. This suggests that the GPi neurons involved in the planning of movement communicate information using an emergence of oscillations in the gamma-band.

Original languageEnglish (US)
Title of host publication33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Pages4179-4182
Number of pages4
DOIs
StatePublished - Dec 26 2011
Externally publishedYes
Event33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States
Duration: Aug 30 2011Sep 3 2011

Other

Other33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
CountryUnited States
CityBoston, MA
Period8/30/119/3/11

Fingerprint

Globus Pallidus
Neurons
Modulation
Planning
Motor Cortex
Basal Ganglia
Primates
Tuning

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Saxena, S., Gale, J. T., Eskandar, E. N., & Sarma, S. V. (2011). Modulations in the oscillatory activity of the Globus Pallidus internus neurons during a behavioral task-A point process analysis. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 (pp. 4179-4182). [6091037] https://doi.org/10.1109/IEMBS.2011.6091037

Modulations in the oscillatory activity of the Globus Pallidus internus neurons during a behavioral task-A point process analysis. / Saxena, Shreya; Gale, John T.; Eskandar, Emad N.; Sarma, Sridevi V.

33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. 2011. p. 4179-4182 6091037.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Saxena, S, Gale, JT, Eskandar, EN & Sarma, SV 2011, Modulations in the oscillatory activity of the Globus Pallidus internus neurons during a behavioral task-A point process analysis. in 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011., 6091037, pp. 4179-4182, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011, Boston, MA, United States, 8/30/11. https://doi.org/10.1109/IEMBS.2011.6091037
Saxena S, Gale JT, Eskandar EN, Sarma SV. Modulations in the oscillatory activity of the Globus Pallidus internus neurons during a behavioral task-A point process analysis. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. 2011. p. 4179-4182. 6091037 https://doi.org/10.1109/IEMBS.2011.6091037
Saxena, Shreya ; Gale, John T. ; Eskandar, Emad N. ; Sarma, Sridevi V. / Modulations in the oscillatory activity of the Globus Pallidus internus neurons during a behavioral task-A point process analysis. 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. 2011. pp. 4179-4182
@inproceedings{f2e1aca916684ffaa18300ebeef62f9a,
title = "Modulations in the oscillatory activity of the Globus Pallidus internus neurons during a behavioral task-A point process analysis",
abstract = "The behavioral state of a subject is hypothesized to be reflected in the oscillatory modulations of the spiking activity of certain groups of neurons. In particular, the beta- and gamma-bands have been experimentally shown to be related to movement in the motor cortex and parts of the basal ganglia. Here, we analyze the relationship between directional tuning and oscillations in the beta- and gamma-bands of the neurons in the Globus Pallidus internus (GPi) of two healthy nonhuman primates during a radial center-out motor task. We find that, during the planning stages of the movement, the percentage of directionally tuned neurons displaying gamma oscillations increases when compared to the percentage of directionally tuned neurons displaying beta oscillations. A similar trend is not seen in non-directionally tuned neurons. This suggests that the GPi neurons involved in the planning of movement communicate information using an emergence of oscillations in the gamma-band.",
author = "Shreya Saxena and Gale, {John T.} and Eskandar, {Emad N.} and Sarma, {Sridevi V.}",
year = "2011",
month = "12",
day = "26",
doi = "10.1109/IEMBS.2011.6091037",
language = "English (US)",
isbn = "9781424441211",
pages = "4179--4182",
booktitle = "33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011",

}

TY - GEN

T1 - Modulations in the oscillatory activity of the Globus Pallidus internus neurons during a behavioral task-A point process analysis

AU - Saxena, Shreya

AU - Gale, John T.

AU - Eskandar, Emad N.

AU - Sarma, Sridevi V.

PY - 2011/12/26

Y1 - 2011/12/26

N2 - The behavioral state of a subject is hypothesized to be reflected in the oscillatory modulations of the spiking activity of certain groups of neurons. In particular, the beta- and gamma-bands have been experimentally shown to be related to movement in the motor cortex and parts of the basal ganglia. Here, we analyze the relationship between directional tuning and oscillations in the beta- and gamma-bands of the neurons in the Globus Pallidus internus (GPi) of two healthy nonhuman primates during a radial center-out motor task. We find that, during the planning stages of the movement, the percentage of directionally tuned neurons displaying gamma oscillations increases when compared to the percentage of directionally tuned neurons displaying beta oscillations. A similar trend is not seen in non-directionally tuned neurons. This suggests that the GPi neurons involved in the planning of movement communicate information using an emergence of oscillations in the gamma-band.

AB - The behavioral state of a subject is hypothesized to be reflected in the oscillatory modulations of the spiking activity of certain groups of neurons. In particular, the beta- and gamma-bands have been experimentally shown to be related to movement in the motor cortex and parts of the basal ganglia. Here, we analyze the relationship between directional tuning and oscillations in the beta- and gamma-bands of the neurons in the Globus Pallidus internus (GPi) of two healthy nonhuman primates during a radial center-out motor task. We find that, during the planning stages of the movement, the percentage of directionally tuned neurons displaying gamma oscillations increases when compared to the percentage of directionally tuned neurons displaying beta oscillations. A similar trend is not seen in non-directionally tuned neurons. This suggests that the GPi neurons involved in the planning of movement communicate information using an emergence of oscillations in the gamma-band.

UR - http://www.scopus.com/inward/record.url?scp=84055176131&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84055176131&partnerID=8YFLogxK

U2 - 10.1109/IEMBS.2011.6091037

DO - 10.1109/IEMBS.2011.6091037

M3 - Conference contribution

SN - 9781424441211

SP - 4179

EP - 4182

BT - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011

ER -