Secreted and cell-associated plasminogen activator was measured in human skin fibroblasts infected with mycoplasmas. The infected fibroblasts exhibited significantly higher levels of secreted and cell-associated plasminogen activator activity compared to uninfected skin fibroblasts. Subconfluent infected fibroblasts had increased plasminogen activator activity compared to confluent infected fibroblasts. Plasminogen activator may be important in tissue destruction in disease states in which mycoplasma infection has been implicated.
|Original language||English (US)|
|Number of pages||4|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|Publication status||Published - Jul 1983|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)