Model of upper airway flow restriction in children with obstructive sleep APNEA

D. M. Wootton, A. Guez, P. Vaidyanathan, D. Avinash, J. R. Stablum, J. M. McDonough, J. K. Udupa, R. Arens

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations


Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.

Original languageEnglish (US)
Title of host publicationProceedings of the IEEE 29th Annual Northeast Bioengineering Conference
EditorsStanley Reisman, Richard Foulds, Bruno Mantilla
PublisherInstitute of Electrical and Electronics Engineers Inc.
Number of pages2
ISBN (Electronic)0780377672
StatePublished - 2003
Externally publishedYes
Event29th IEEE Annual Northeast Bioengineering Conference, NEBC 2003 - Newark, United States
Duration: Mar 22 2003Mar 23 2003

Publication series

NameProceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
ISSN (Print)1071-121X
ISSN (Electronic)2160-7001


Other29th IEEE Annual Northeast Bioengineering Conference, NEBC 2003
CountryUnited States


  • Anatomy
  • Computational fluid dynamics
  • Fluid flow control
  • Image processing
  • Image segmentation
  • Immune system
  • Magnetic resonance imaging
  • Pediatrics
  • Pressure control
  • Sleep apnea

ASJC Scopus subject areas

  • Bioengineering

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