Model of upper airway flow restriction in children with obstructive sleep apnea

D. M. Wootton; A. Guez; P. Vaidyanathan; D. Avinash; J. R. Stablum; J. M. McDonough; J. K. Udupa; R. Arens

Model of upper airway flow restriction in children with obstructive sleep apnea

D. M. Wootton, A. Guez, P. Vaidyanathan, D. Avinash, J. R. Stablum, J. M. McDonough, J. K. Udupa, R. Arens

Research output: Contribution to journal › Conference article › peer-review

Abstract

Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.

Original language	English (US)
Pages (from-to)	217-218
Number of pages	2
Journal	Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
State	Published - 2003
Externally published	Yes
Event	Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference - Newark, NJ, United States Duration: Mar 22 2003 → Mar 23 2003

Keywords

Anatomy
CFD
Computer Model
Fluid Mechanics
MRI
Obstructive Sleep Apnea

ASJC Scopus subject areas

Chemical Engineering(all)
Bioengineering

Cite this

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title = "Model of upper airway flow restriction in children with obstructive sleep apnea",

abstract = "Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.",

keywords = "Anatomy, CFD, Computer Model, Fluid Mechanics, MRI, Obstructive Sleep Apnea",

author = "Wootton, {D. M.} and A. Guez and P. Vaidyanathan and D. Avinash and Stablum, {J. R.} and McDonough, {J. M.} and Udupa, {J. K.} and R. Arens",

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language = "English (US)",

pages = "217--218",

journal = "Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC",

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note = "Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference ; Conference date: 22-03-2003 Through 23-03-2003",

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T1 - Model of upper airway flow restriction in children with obstructive sleep apnea

AU - Wootton, D. M.

AU - Guez, A.

AU - Vaidyanathan, P.

AU - Avinash, D.

AU - Stablum, J. R.

AU - McDonough, J. M.

AU - Udupa, J. K.

AU - Arens, R.

PY - 2003

Y1 - 2003

N2 - Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.

AB - Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.

KW - Anatomy

KW - CFD

KW - Computer Model

KW - Fluid Mechanics

KW - MRI

KW - Obstructive Sleep Apnea

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AN - SCOPUS:84943385596

SN - 1071-121X

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JO - Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC

JF - Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC

T2 - Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference

Y2 - 22 March 2003 through 23 March 2003

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Model of upper airway flow restriction in children with obstructive sleep apnea

Abstract

Keywords

ASJC Scopus subject areas

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