Abstract
Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.
| Original language | English (US) |
|---|---|
| Title of host publication | Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 217-218 |
| Number of pages | 2 |
| Volume | 2003-January |
| ISBN (Print) | 0780377672 |
| DOIs | |
| State | Published - 2003 |
| Externally published | Yes |
| Event | 29th IEEE Annual Northeast Bioengineering Conference, NEBC 2003 - Newark, United States Duration: Mar 22 2003 → Mar 23 2003 |
Other
| Other | 29th IEEE Annual Northeast Bioengineering Conference, NEBC 2003 |
|---|---|
| Country | United States |
| City | Newark |
| Period | 3/22/03 → 3/23/03 |
Fingerprint
Keywords
- Anatomy
- Computational fluid dynamics
- Fluid flow control
- Image processing
- Image segmentation
- Immune system
- Magnetic resonance imaging
- Pediatrics
- Pressure control
- Sleep apnea
ASJC Scopus subject areas
- Bioengineering
Cite this
Model of upper airway flow restriction in children with obstructive sleep APNEA. / Wootton, D. M.; Guez, A.; Vaidyanathan, P.; Avinash, D.; Stablum, J. R.; McDonough, J. M.; Udupa, J. K.; Arens, Raanan.
Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC. Vol. 2003-January Institute of Electrical and Electronics Engineers Inc., 2003. p. 217-218 1216071.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Model of upper airway flow restriction in children with obstructive sleep APNEA
AU - Wootton, D. M.
AU - Guez, A.
AU - Vaidyanathan, P.
AU - Avinash, D.
AU - Stablum, J. R.
AU - McDonough, J. M.
AU - Udupa, J. K.
AU - Arens, Raanan
PY - 2003
Y1 - 2003
N2 - Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.
AB - Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.
KW - Anatomy
KW - Computational fluid dynamics
KW - Fluid flow control
KW - Image processing
KW - Image segmentation
KW - Immune system
KW - Magnetic resonance imaging
KW - Pediatrics
KW - Pressure control
KW - Sleep apnea
UR - http://www.scopus.com/inward/record.url?scp=84943385596&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84943385596&partnerID=8YFLogxK
U2 - 10.1109/NEBC.2003.1216071
DO - 10.1109/NEBC.2003.1216071
M3 - Conference contribution
AN - SCOPUS:84943385596
SN - 0780377672
VL - 2003-January
SP - 217
EP - 218
BT - Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
PB - Institute of Electrical and Electronics Engineers Inc.
ER -