Model of upper airway flow restriction in children with obstructive sleep apnea

D. M. Wootton, A. Guez, P. Vaidyanathan, D. Avinash, J. R. Stablum, J. M. McDonough, J. K. Udupa, Raanan Arens

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.

Original languageEnglish (US)
Title of host publicationBioengineering, Proceedings of the Northeast Conference
EditorsS. Reisman, R. Foulds, B. Mantilla
Pages217-218
Number of pages2
StatePublished - 2003
Externally publishedYes
EventProceedings of the IEEE 29th Annual Northeast Bioengineering Conference - Newark, NJ, United States
Duration: Mar 22 2003Mar 23 2003

Other

OtherProceedings of the IEEE 29th Annual Northeast Bioengineering Conference
CountryUnited States
CityNewark, NJ
Period3/22/033/23/03

Fingerprint

Pressure drop
Magnetic resonance
Turbulent flow
Flow rate
Sleep

Keywords

  • Anatomy
  • CFD
  • Computer Model
  • Fluid Mechanics
  • MRI
  • Obstructive Sleep Apnea

ASJC Scopus subject areas

  • Chemical Engineering(all)

Cite this

Wootton, D. M., Guez, A., Vaidyanathan, P., Avinash, D., Stablum, J. R., McDonough, J. M., ... Arens, R. (2003). Model of upper airway flow restriction in children with obstructive sleep apnea. In S. Reisman, R. Foulds, & B. Mantilla (Eds.), Bioengineering, Proceedings of the Northeast Conference (pp. 217-218)

Model of upper airway flow restriction in children with obstructive sleep apnea. / Wootton, D. M.; Guez, A.; Vaidyanathan, P.; Avinash, D.; Stablum, J. R.; McDonough, J. M.; Udupa, J. K.; Arens, Raanan.

Bioengineering, Proceedings of the Northeast Conference. ed. / S. Reisman; R. Foulds; B. Mantilla. 2003. p. 217-218.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wootton, DM, Guez, A, Vaidyanathan, P, Avinash, D, Stablum, JR, McDonough, JM, Udupa, JK & Arens, R 2003, Model of upper airway flow restriction in children with obstructive sleep apnea. in S Reisman, R Foulds & B Mantilla (eds), Bioengineering, Proceedings of the Northeast Conference. pp. 217-218, Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference, Newark, NJ, United States, 3/22/03.
Wootton DM, Guez A, Vaidyanathan P, Avinash D, Stablum JR, McDonough JM et al. Model of upper airway flow restriction in children with obstructive sleep apnea. In Reisman S, Foulds R, Mantilla B, editors, Bioengineering, Proceedings of the Northeast Conference. 2003. p. 217-218
Wootton, D. M. ; Guez, A. ; Vaidyanathan, P. ; Avinash, D. ; Stablum, J. R. ; McDonough, J. M. ; Udupa, J. K. ; Arens, Raanan. / Model of upper airway flow restriction in children with obstructive sleep apnea. Bioengineering, Proceedings of the Northeast Conference. editor / S. Reisman ; R. Foulds ; B. Mantilla. 2003. pp. 217-218
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