Mobile brain/body imaging (MoBI): High-density electrical mapping of inhibitory processes during walking

Pierfilippo De Sanctis, John S. Butler, Jason M. Green, Adam C. Snyder, John J. Foxe

Research output: Chapter in Book/Report/Conference proceedingConference contribution

17 Scopus citations

Abstract

The present study investigated the feasibility of acquiring high-density event-related brain potential (ERP) recordings during treadmill walking in human subjects. The work builds upon recent studies testing the applicability of real-world tasks while obtaining electroencephalographic (EEG) recordings. Participants performed a response inhibition GO/NOGO task - designed to evoke a P3 component for correct response inhibitions and an error-related negativity (ERN) for incorrect commission errors - while speed of walking was experimentally manipulated. Robust P3 and ERN components were obtained under all experimental conditions - while participants were sitting, walking at moderate speed (2.4 km/hour), or walking rapidly (5 km/hour). Signal-to-noise ratios were remarkably similar across conditions, pointing to the feasibility of high-fidelity ERP recordings under relatively vigorous activity regimens. There is considerable research and clinical motivation to obtain high quality neurophysiological measures under more naturalistic environmental settings such as these. Strong links between cognitive load and gait abnormalities are seen in a number of clinical populations and these MoBI technologies provide highly promising methods for gaining insights into the underlying pathophysiology.

Original languageEnglish (US)
Title of host publication2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012
Pages1542-1545
Number of pages4
DOIs
StatePublished - Dec 14 2012
Event34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012 - San Diego, CA, United States
Duration: Aug 28 2012Sep 1 2012

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Other

Other34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
CountryUnited States
CitySan Diego, CA
Period8/28/129/1/12

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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    De Sanctis, P., Butler, J. S., Green, J. M., Snyder, A. C., & Foxe, J. J. (2012). Mobile brain/body imaging (MoBI): High-density electrical mapping of inhibitory processes during walking. In 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012 (pp. 1542-1545). [6346236] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2012.6346236