Mitogenic induction of macrophage and neutrophil proliferation in human tonsils

Julian Melamed, Arye Rubinstein

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A spontaneous and mitogen-induced in vitro release of colony-stimulating activity from human tonsillar cells was observed. This release was absent when T cells were depleted from the cell suspension. Supernates containing colony-stimulating activity induced the proliferation and differentiation of tonsillar precursor cells into monocytes and granulocytes. The maturation and proliferation of monocytes and granulocytes were followed by a continuous flow staining technique, cytochemistry, electro-optical measurement, and signal logic processing employing the automated Hemalog D cell differential counter.

Original languageEnglish (US)
Pages (from-to)406-412
Number of pages7
JournalClinical Immunology and Immunopathology
Volume11
Issue number4
DOIs
StatePublished - 1978

Fingerprint

Palatine Tonsil
Monocytes
Neutrophils
Macrophages
Granulocyte Precursor Cells
Histocytochemistry
Somatostatin-Secreting Cells
Mitogens
Granulocytes
Human Activities
Suspensions
Staining and Labeling
T-Lymphocytes
In Vitro Techniques

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Pathology and Forensic Medicine

Cite this

Mitogenic induction of macrophage and neutrophil proliferation in human tonsils. / Melamed, Julian; Rubinstein, Arye.

In: Clinical Immunology and Immunopathology, Vol. 11, No. 4, 1978, p. 406-412.

Research output: Contribution to journalArticle

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