Minimizing the Relationship between Early Formula Use and Breastfeeding Cessation by Limiting Formula Volume

Valerie J. Flaherman, Michelle McKean, Elizabeth Braunreuther, Laura R. Kair, Michael D. Cabana

Research output: Contribution to journalArticle

Abstract

Objective: Early exposure to formula can interfere with successful long-term breastfeeding. The objective of this study was to determine whether limiting the volume of formula used in the first month attenuates formula's detrimental impact on long-term breastfeeding success. Materials and Methods: Using detailed data on dietary intake from a randomized clinical trial, we conducted a secondary analysis of the association between volume of formula received in the first month and breastfeeding cessation before 6 and 12 months of age. We used descriptive statistics and multivariable logistic regression, respectively, to explore this association without and with adjustment for demographic and clinical predictors of infant feeding. Results: Among 199 breastfeeding infants, 80 (40%) received formula daily at 1 month of age, and breastfeeding cessation before 6 and 12 months of age was higher for these infants (46% and 67%) than for those breastfed exclusively (6% and 27%) (p < 0.0005 for each). The risk of cessation did not differ between those who received ≤4 fl oz daily in the first month (11%) and those who did not receive formula in the first month (6%) (p = 0.42). Adjusting for gestational age, race/ethnicity, income, and intention to breastfeed exclusively, the odds ratio for the outcome of cessation before 6 months was 1.15 (95% confidence interval = 0.20-6.67) for infants who received ≤4 fl oz daily compared with those who breastfed exclusively. Conclusion: Limiting formula volumes to ≤4 fl oz daily may attenuate the deleterious association between early formula use and subsequent successful breastfeeding.

Original languageEnglish (US)
Pages (from-to)533-537
Number of pages5
JournalBreastfeeding Medicine
Volume14
Issue number8
DOIs
StatePublished - Oct 2019
Externally publishedYes

Fingerprint

Breast Feeding
Gestational Age
Randomized Controlled Trials
Logistic Models
Odds Ratio
Demography
Confidence Intervals

Keywords

  • breastfeeding
  • infant formula
  • newborn

ASJC Scopus subject areas

  • Pediatrics
  • Health Policy
  • Obstetrics and Gynecology
  • Maternity and Midwifery

Cite this

Minimizing the Relationship between Early Formula Use and Breastfeeding Cessation by Limiting Formula Volume. / Flaherman, Valerie J.; McKean, Michelle; Braunreuther, Elizabeth; Kair, Laura R.; Cabana, Michael D.

In: Breastfeeding Medicine, Vol. 14, No. 8, 10.2019, p. 533-537.

Research output: Contribution to journalArticle

Flaherman, Valerie J. ; McKean, Michelle ; Braunreuther, Elizabeth ; Kair, Laura R. ; Cabana, Michael D. / Minimizing the Relationship between Early Formula Use and Breastfeeding Cessation by Limiting Formula Volume. In: Breastfeeding Medicine. 2019 ; Vol. 14, No. 8. pp. 533-537.
@article{07739e1e4a994c90a60c512ed019c934,
title = "Minimizing the Relationship between Early Formula Use and Breastfeeding Cessation by Limiting Formula Volume",
abstract = "Objective: Early exposure to formula can interfere with successful long-term breastfeeding. The objective of this study was to determine whether limiting the volume of formula used in the first month attenuates formula's detrimental impact on long-term breastfeeding success. Materials and Methods: Using detailed data on dietary intake from a randomized clinical trial, we conducted a secondary analysis of the association between volume of formula received in the first month and breastfeeding cessation before 6 and 12 months of age. We used descriptive statistics and multivariable logistic regression, respectively, to explore this association without and with adjustment for demographic and clinical predictors of infant feeding. Results: Among 199 breastfeeding infants, 80 (40{\%}) received formula daily at 1 month of age, and breastfeeding cessation before 6 and 12 months of age was higher for these infants (46{\%} and 67{\%}) than for those breastfed exclusively (6{\%} and 27{\%}) (p < 0.0005 for each). The risk of cessation did not differ between those who received ≤4 fl oz daily in the first month (11{\%}) and those who did not receive formula in the first month (6{\%}) (p = 0.42). Adjusting for gestational age, race/ethnicity, income, and intention to breastfeed exclusively, the odds ratio for the outcome of cessation before 6 months was 1.15 (95{\%} confidence interval = 0.20-6.67) for infants who received ≤4 fl oz daily compared with those who breastfed exclusively. Conclusion: Limiting formula volumes to ≤4 fl oz daily may attenuate the deleterious association between early formula use and subsequent successful breastfeeding.",
keywords = "breastfeeding, infant formula, newborn",
author = "Flaherman, {Valerie J.} and Michelle McKean and Elizabeth Braunreuther and Kair, {Laura R.} and Cabana, {Michael D.}",
year = "2019",
month = "10",
doi = "10.1089/bfm.2019.0055",
language = "English (US)",
volume = "14",
pages = "533--537",
journal = "Breastfeeding Medicine",
issn = "1556-8253",
publisher = "Mary Ann Liebert Inc.",
number = "8",

}

TY - JOUR

T1 - Minimizing the Relationship between Early Formula Use and Breastfeeding Cessation by Limiting Formula Volume

AU - Flaherman, Valerie J.

AU - McKean, Michelle

AU - Braunreuther, Elizabeth

AU - Kair, Laura R.

AU - Cabana, Michael D.

PY - 2019/10

Y1 - 2019/10

N2 - Objective: Early exposure to formula can interfere with successful long-term breastfeeding. The objective of this study was to determine whether limiting the volume of formula used in the first month attenuates formula's detrimental impact on long-term breastfeeding success. Materials and Methods: Using detailed data on dietary intake from a randomized clinical trial, we conducted a secondary analysis of the association between volume of formula received in the first month and breastfeeding cessation before 6 and 12 months of age. We used descriptive statistics and multivariable logistic regression, respectively, to explore this association without and with adjustment for demographic and clinical predictors of infant feeding. Results: Among 199 breastfeeding infants, 80 (40%) received formula daily at 1 month of age, and breastfeeding cessation before 6 and 12 months of age was higher for these infants (46% and 67%) than for those breastfed exclusively (6% and 27%) (p < 0.0005 for each). The risk of cessation did not differ between those who received ≤4 fl oz daily in the first month (11%) and those who did not receive formula in the first month (6%) (p = 0.42). Adjusting for gestational age, race/ethnicity, income, and intention to breastfeed exclusively, the odds ratio for the outcome of cessation before 6 months was 1.15 (95% confidence interval = 0.20-6.67) for infants who received ≤4 fl oz daily compared with those who breastfed exclusively. Conclusion: Limiting formula volumes to ≤4 fl oz daily may attenuate the deleterious association between early formula use and subsequent successful breastfeeding.

AB - Objective: Early exposure to formula can interfere with successful long-term breastfeeding. The objective of this study was to determine whether limiting the volume of formula used in the first month attenuates formula's detrimental impact on long-term breastfeeding success. Materials and Methods: Using detailed data on dietary intake from a randomized clinical trial, we conducted a secondary analysis of the association between volume of formula received in the first month and breastfeeding cessation before 6 and 12 months of age. We used descriptive statistics and multivariable logistic regression, respectively, to explore this association without and with adjustment for demographic and clinical predictors of infant feeding. Results: Among 199 breastfeeding infants, 80 (40%) received formula daily at 1 month of age, and breastfeeding cessation before 6 and 12 months of age was higher for these infants (46% and 67%) than for those breastfed exclusively (6% and 27%) (p < 0.0005 for each). The risk of cessation did not differ between those who received ≤4 fl oz daily in the first month (11%) and those who did not receive formula in the first month (6%) (p = 0.42). Adjusting for gestational age, race/ethnicity, income, and intention to breastfeed exclusively, the odds ratio for the outcome of cessation before 6 months was 1.15 (95% confidence interval = 0.20-6.67) for infants who received ≤4 fl oz daily compared with those who breastfed exclusively. Conclusion: Limiting formula volumes to ≤4 fl oz daily may attenuate the deleterious association between early formula use and subsequent successful breastfeeding.

KW - breastfeeding

KW - infant formula

KW - newborn

UR - http://www.scopus.com/inward/record.url?scp=85073087975&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85073087975&partnerID=8YFLogxK

U2 - 10.1089/bfm.2019.0055

DO - 10.1089/bfm.2019.0055

M3 - Article

C2 - 31314569

AN - SCOPUS:85073087975

VL - 14

SP - 533

EP - 537

JO - Breastfeeding Medicine

JF - Breastfeeding Medicine

SN - 1556-8253

IS - 8

ER -