Microwave Treatments for Prostate Disease

Fred Sterzer, Daniel D. Mawhinney, Jozef Mendecki, Arnold Melman, Esther Friedenthal

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

This paper describes three novel microwave techniques that show promise for being useful in treating diseases of the prostate. They are: microwave urethroplasty for providing immediate symptomatic relief of urinary obstructions caused by benign prostatic hyperthrophy—this technique uses microwave balloon catheters for producing biological stems in the urethra. Initial results obtained in an Federal Drug Administration approved Phase I clinical trial are highly encouraging, hyperthermia produced in the prostate by dual microwave balloon catheters—when combined with external beam radiation or implanted radioactive seeds, this technique has the potential of improving local recurrence rates of prostate cancer over the rates that are obtained when only radiation treatments are given, and microwave poration therapy—a therapy that, when combined with either systemic or locally administered chemotherapy, has been shown to be effective in shrinking implanted prostatic tumors in rats. The potential clinical advantages of microwave poration/chemotherapy over electrochemotherapy using dc pulses for treating cancers are discussed.

Original languageEnglish (US)
Pages (from-to)1885-1891
Number of pages7
JournalIEEE Transactions on Microwave Theory and Techniques
Volume48
Issue number11
DOIs
StatePublished - Nov 2000

Keywords

  • Benign prostatic hyperthrophy
  • hyperthermia
  • poration
  • prostate cancer

ASJC Scopus subject areas

  • Radiation
  • Condensed Matter Physics
  • Electrical and Electronic Engineering

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  • Cite this

    Sterzer, F., Mawhinney, D. D., Mendecki, J., Melman, A., & Friedenthal, E. (2000). Microwave Treatments for Prostate Disease. IEEE Transactions on Microwave Theory and Techniques, 48(11), 1885-1891. https://doi.org/10.1109/22.883867