Microwave treatments for prostate disease

Fred Sterzer, Jozef Mendecki, Daniel D. Mawhinney, Esther Friedenthal, Arnold Melman

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This paper describes three novel microwave techniques that show promise for being useful in treating diseases of the prostate. They are: microwave urethroplasty for providing immediate symptomatic relief of urinary obstructions caused by benign prostatic hyperthrophy-this technique uses microwave balloon catheters for producing biological stems in the urethra. Initial results obtained in an Federal Drug Administration approved Phase I clinical trial are highly encouraging, hyperthermia produced in the prostate by dual microwave balloon catheters-when combined with external beam radiation or implanted radioactive seeds, this technique has the potential of improving local recurrence rates of prostate cancer over the rates that are obtained when only radiation treatments are given, and microwave poration therapy-a therapy that, when combined with either systemic or locally administered chemotherapy, has been shown to be effective in shrinking implanted prostatic tumors in rats. The potential clinical advantages of microwave poration/chemotherapy over electrochemotherapy using dc pulses for treating cancers are discussed.

Original languageEnglish (US)
Pages (from-to)1885-1991
Number of pages107
JournalIEEE Transactions on Microwave Theory and Techniques
Volume48
Issue number1 PART 1
StatePublished - 2000

Fingerprint

Microwaves
microwaves
Chemotherapy
Catheters
Balloons
balloons
chemotherapy
therapy
cancer
Radiation
hyperthermia
stems
rats
Seed
Rats
Tumors
seeds
drugs
tumors
radiation

Keywords

  • Benign prostatic hyperthrophy
  • Hyperthermia
  • Poration
  • Prostate cancer

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

Cite this

Sterzer, F., Mendecki, J., Mawhinney, D. D., Friedenthal, E., & Melman, A. (2000). Microwave treatments for prostate disease. IEEE Transactions on Microwave Theory and Techniques, 48(1 PART 1), 1885-1991.

Microwave treatments for prostate disease. / Sterzer, Fred; Mendecki, Jozef; Mawhinney, Daniel D.; Friedenthal, Esther; Melman, Arnold.

In: IEEE Transactions on Microwave Theory and Techniques, Vol. 48, No. 1 PART 1, 2000, p. 1885-1991.

Research output: Contribution to journalArticle

Sterzer, F, Mendecki, J, Mawhinney, DD, Friedenthal, E & Melman, A 2000, 'Microwave treatments for prostate disease', IEEE Transactions on Microwave Theory and Techniques, vol. 48, no. 1 PART 1, pp. 1885-1991.
Sterzer F, Mendecki J, Mawhinney DD, Friedenthal E, Melman A. Microwave treatments for prostate disease. IEEE Transactions on Microwave Theory and Techniques. 2000;48(1 PART 1):1885-1991.
Sterzer, Fred ; Mendecki, Jozef ; Mawhinney, Daniel D. ; Friedenthal, Esther ; Melman, Arnold. / Microwave treatments for prostate disease. In: IEEE Transactions on Microwave Theory and Techniques. 2000 ; Vol. 48, No. 1 PART 1. pp. 1885-1991.
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