Microarray technology in the investigation of diseases of myocardium with special reference to infection

Shankar Mukherjee, Thomas J. Belbin, David C. Spray, Aparna Mukhopadhyay, Nagajyothi, Louis M. Weiss, Herbert B. Tanowitz

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Microarrays are now routinely employed to characterize gene expression of thousands of genes from a single hybridization. The genome wide gene expression profile aids in the understanding of genes that may be regulated in a particular pathological condition. This paper provides an overview of microarray technology and its recent developments followed by its usage in studies of cardiovascular disease and how it pertains to viral and parasitic infections of the heart.

Original languageEnglish (US)
Pages (from-to)1802-1813
Number of pages12
JournalFrontiers in Bioscience
Volume11
Issue number2 P.1591-2006
DOIs
StatePublished - Jan 1 2006

Keywords

  • Chagas disease
  • Heart Disease
  • Infection
  • Micro-organism
  • Microarray
  • Parasite
  • Review

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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