Methotrexate treatment of Wegener granulomatosis in children

B. S. Gottlieb, L. C. Miller, N. T. Ilowite

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Abstract

Wegener granulomatosis traditionally has been treated with glucocorticoids and cyclophosphamide. Both the disease and its treatments are associated with significant morbidity and mortality rates. There has been an effort to find effective but less toxic alternative treatments. We describe three children with Wegener granulomatosis who responded well to treatment with glucocorticoids and methotrexate, similar to a regimen used in adults.

Original languageEnglish (US)
Pages (from-to)604-607
Number of pages4
JournalJournal of Pediatrics
Volume129
Issue number4
DOIs
Publication statusPublished - Jan 1 1996

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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