Metastatic breast carcinoma to bone disguised by osteopoikilosis

J. G. Kennedy, J. R. Donahue, H. Aydin, B. H. Hoang, A. Huvos, C. Morris

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

A case of metastatic lobular carcinoma of the breast in conjunction with osteopoikilosis is described. Widespread diffuse sclerotic bone lesions were identified on radiographs in a patient with breast carcinoma. In addition computed tomography demonstrated discrete spherical areas of increased density throughout the skeleton manifest typically by osteopoikilosis. No systemic symptoms were evident, blood parameters were normal and the lesions did not demonstrate any increased uptake of technetium on bone scan. An iliac crest bone biopsy, however, revealed metastatic disease in addition to osteopoikilosis. Conventional radiological investigations may not delineate metastasis on a background of bone dysplasia.

Original languageEnglish (US)
Pages (from-to)240-243
Number of pages4
JournalSkeletal Radiology
Volume32
Issue number4
DOIs
StatePublished - Apr 1 2003

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Keywords

  • Metastatic breast cancer
  • Osteopoikilosis
  • Radiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Kennedy, J. G., Donahue, J. R., Aydin, H., Hoang, B. H., Huvos, A., & Morris, C. (2003). Metastatic breast carcinoma to bone disguised by osteopoikilosis. Skeletal Radiology, 32(4), 240-243. https://doi.org/10.1007/s00256-002-0605-x