Metabolism of the diaminoantifolates: Biosynthesis and pharmacology of the 7-hydroxyl and polyglutamyl metabolites of methotrexate and related antifolates

Larry H. Matherly, Richard Seither, I. David Goldman

Research output: Contribution to journalArticle

26 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)27-56
Number of pages30
JournalPharmacology and Therapeutics
Volume35
Issue number1-2
DOIs
StatePublished - 1987
Externally publishedYes

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Aminopterin
Polyglutamic Acid
Folic Acid Antagonists
Hydroxylation
Biotransformation
Methotrexate
Hydroxyl Radical
Pharmacology

ASJC Scopus subject areas

  • Pharmacology

Cite this

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title = "Metabolism of the diaminoantifolates: Biosynthesis and pharmacology of the 7-hydroxyl and polyglutamyl metabolites of methotrexate and related antifolates",
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AU - Seither, Richard

AU - Goldman, I. David

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VL - 35

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