Metabolic strugGLS after FLT3 inhibition in AML

Samuel J. Taylor, Ulrich G. Steidl

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

In this issue of Blood, Gallipoli et al report that by performing an elegant clustered regularly interspaced short palindromic repeats (CRISPR) screen of FLT3 internal tandem duplication–positive (FLT3-ITD1) acute myeloid leukemia (AML) cells, they have identified that FLT3 inhibition exposes a therapeutically relevant metabolic dependency on glutaminolysis.

Original languageEnglish (US)
Pages (from-to)1631-1632
Number of pages2
JournalBlood
Volume131
Issue number15
DOIs
Publication statusPublished - Apr 12 2018

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ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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