Mesenteric ischemia: a cause of increased gastric blood flow, hyperacidity, and acute gastric ulceration.

S. J. Boley, M. I. Cohen, P. R. Winslow, N. H. Becker, W. Treiber, H. McNamara, F. J. Veith, M. L. Gliedman

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

1. The effects of acute diminution in superior mesenteric arterial flow on gastric blood flow and acidity were studied in 17 anesthetized dogs. 2. Acute mesenteric ischemia produced a rise in celiac and gastric blood flow, higher total acid concentrations, and increased total acid secretion. Ischemia of 12 hours' duration was associated with gross gastric bleeding and in one animal acute superficial gastric ulcerations. 3. The rise in celiac and gastric blood flow appeared to be a hemodynamic response to the fall in mesenteric arterial pressure and was minimized by ligation of the major artery connecting the mesenteric and celiac vascular beds. 4. The increased acid concentration and secretion appeared to be directly related to, and a result of, the augmented gastric blood flow. 5. A direct causal relationship between mesenteric vascular occlusions and subsequent upper gastrointestinal bleeding is suggested.

Original languageEnglish (US)
Pages (from-to)222-230
Number of pages9
JournalSurgery
Volume68
Issue number1
StatePublished - Jul 1970

Fingerprint

Stomach
Abdomen
Acids
Mesenteric Vascular Occlusion
Celiac Artery
Hemorrhage
Mesenteric Arteries
Ligation
Blood Vessels
Mesenteric Ischemia
Arterial Pressure
Ischemia
Hemodynamics
Dogs

ASJC Scopus subject areas

  • Surgery

Cite this

Boley, S. J., Cohen, M. I., Winslow, P. R., Becker, N. H., Treiber, W., McNamara, H., ... Gliedman, M. L. (1970). Mesenteric ischemia: a cause of increased gastric blood flow, hyperacidity, and acute gastric ulceration. Surgery, 68(1), 222-230.

Mesenteric ischemia : a cause of increased gastric blood flow, hyperacidity, and acute gastric ulceration. / Boley, S. J.; Cohen, M. I.; Winslow, P. R.; Becker, N. H.; Treiber, W.; McNamara, H.; Veith, F. J.; Gliedman, M. L.

In: Surgery, Vol. 68, No. 1, 07.1970, p. 222-230.

Research output: Contribution to journalArticle

Boley, SJ, Cohen, MI, Winslow, PR, Becker, NH, Treiber, W, McNamara, H, Veith, FJ & Gliedman, ML 1970, 'Mesenteric ischemia: a cause of increased gastric blood flow, hyperacidity, and acute gastric ulceration.', Surgery, vol. 68, no. 1, pp. 222-230.
Boley, S. J. ; Cohen, M. I. ; Winslow, P. R. ; Becker, N. H. ; Treiber, W. ; McNamara, H. ; Veith, F. J. ; Gliedman, M. L. / Mesenteric ischemia : a cause of increased gastric blood flow, hyperacidity, and acute gastric ulceration. In: Surgery. 1970 ; Vol. 68, No. 1. pp. 222-230.
@article{fa63a639da734289a7953269407b607f,
title = "Mesenteric ischemia: a cause of increased gastric blood flow, hyperacidity, and acute gastric ulceration.",
abstract = "1. The effects of acute diminution in superior mesenteric arterial flow on gastric blood flow and acidity were studied in 17 anesthetized dogs. 2. Acute mesenteric ischemia produced a rise in celiac and gastric blood flow, higher total acid concentrations, and increased total acid secretion. Ischemia of 12 hours' duration was associated with gross gastric bleeding and in one animal acute superficial gastric ulcerations. 3. The rise in celiac and gastric blood flow appeared to be a hemodynamic response to the fall in mesenteric arterial pressure and was minimized by ligation of the major artery connecting the mesenteric and celiac vascular beds. 4. The increased acid concentration and secretion appeared to be directly related to, and a result of, the augmented gastric blood flow. 5. A direct causal relationship between mesenteric vascular occlusions and subsequent upper gastrointestinal bleeding is suggested.",
author = "Boley, {S. J.} and Cohen, {M. I.} and Winslow, {P. R.} and Becker, {N. H.} and W. Treiber and H. McNamara and Veith, {F. J.} and Gliedman, {M. L.}",
year = "1970",
month = "7",
language = "English (US)",
volume = "68",
pages = "222--230",
journal = "Surgery (United States)",
issn = "0039-6060",
publisher = "Mosby Inc.",
number = "1",

}

TY - JOUR

T1 - Mesenteric ischemia

T2 - a cause of increased gastric blood flow, hyperacidity, and acute gastric ulceration.

AU - Boley, S. J.

AU - Cohen, M. I.

AU - Winslow, P. R.

AU - Becker, N. H.

AU - Treiber, W.

AU - McNamara, H.

AU - Veith, F. J.

AU - Gliedman, M. L.

PY - 1970/7

Y1 - 1970/7

N2 - 1. The effects of acute diminution in superior mesenteric arterial flow on gastric blood flow and acidity were studied in 17 anesthetized dogs. 2. Acute mesenteric ischemia produced a rise in celiac and gastric blood flow, higher total acid concentrations, and increased total acid secretion. Ischemia of 12 hours' duration was associated with gross gastric bleeding and in one animal acute superficial gastric ulcerations. 3. The rise in celiac and gastric blood flow appeared to be a hemodynamic response to the fall in mesenteric arterial pressure and was minimized by ligation of the major artery connecting the mesenteric and celiac vascular beds. 4. The increased acid concentration and secretion appeared to be directly related to, and a result of, the augmented gastric blood flow. 5. A direct causal relationship between mesenteric vascular occlusions and subsequent upper gastrointestinal bleeding is suggested.

AB - 1. The effects of acute diminution in superior mesenteric arterial flow on gastric blood flow and acidity were studied in 17 anesthetized dogs. 2. Acute mesenteric ischemia produced a rise in celiac and gastric blood flow, higher total acid concentrations, and increased total acid secretion. Ischemia of 12 hours' duration was associated with gross gastric bleeding and in one animal acute superficial gastric ulcerations. 3. The rise in celiac and gastric blood flow appeared to be a hemodynamic response to the fall in mesenteric arterial pressure and was minimized by ligation of the major artery connecting the mesenteric and celiac vascular beds. 4. The increased acid concentration and secretion appeared to be directly related to, and a result of, the augmented gastric blood flow. 5. A direct causal relationship between mesenteric vascular occlusions and subsequent upper gastrointestinal bleeding is suggested.

UR - http://www.scopus.com/inward/record.url?scp=0014825243&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0014825243&partnerID=8YFLogxK

M3 - Article

C2 - 10483473

AN - SCOPUS:0014825243

VL - 68

SP - 222

EP - 230

JO - Surgery (United States)

JF - Surgery (United States)

SN - 0039-6060

IS - 1

ER -