Mercury and Neurodegeneration

Stephanie J.B. Fretham, Ebany J. Martinez-Finley, Michael Aschner

1 Scopus citations

Abstract

Mercury (Hg) is a naturally occurring, nonessential metal that humans encounter through diet, industry, and natural health products. Hg has wide-reaching effects on the nervous system and is accepted as a neurotoxicant that promotes neurodegeneration and causes neurodevelopmental abnormalities. This chapter discusses sources of Hg exposure, metabolism and dietary interactions, and the biochemical mechanisms through which Hg interferes with neurological function and development.

Original languageEnglish (US)
Title of host publicationBioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease
Subtitle of host publicationPrevention and Therapy
PublisherElsevier Inc.
Pages237-244
Number of pages8
ISBN (Electronic)9780124115293
ISBN (Print)9780124114623
DOIs
StatePublished - Jan 1 2015

Keywords

  • Ethylmercury
  • Mercury
  • Metabolism
  • Methylmercury
  • Neurodevelopment
  • Oxidative stress
  • Thiol

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fretham, S. J. B., Martinez-Finley, E. J., & Aschner, M. (2015). Mercury and Neurodegeneration. In Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease: Prevention and Therapy (pp. 237-244). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-411462-3.00026-6