Menstrual Cycle Hormone Changes Associated with Reproductive Aging and How They May Relate to Symptoms

Amanda Allshouse, Jelena M. Pavlovic, Nanette Santoro

Research output: Contribution to journalReview article

2 Scopus citations


Key cycle changes occur as women transition from reproductive life to menopause, and they can be roughly linked to menopausal staging. It is important to understand the types of studies that inform the current knowledge. Patterns of symptoms within menstrual cycles (sleep, headache) generally favor worsening in association with the perimenstrual phase of the cycle, and patterns of chronic symptoms, such as hot flashes and adverse mood, appear to be worse when hormones are more variable.

Original languageEnglish (US)
Pages (from-to)613-628
Number of pages16
JournalObstetrics and Gynecology Clinics of North America
Issue number4
StatePublished - Dec 1 2018



  • Folliculogenesis
  • Gonadotropins
  • Perimenopause
  • Reproductive aging

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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