Membrane‐associated ribosomes in producing and nonproducing mouse myeloma cells

William Cieplinski, M. D. Scharff

Research output: Contribution to journalArticle

Abstract

Mouse myeloma cell lines synthesize large amounts of immunoglobulin on their membrane‐associated polyribosomes. Variants which no longer synthesize immunoglobulins have been studied and shown to have the same number of tightly bound membrane‐associated polyribosomes as the parental cell lines. These polyribosomes are still active in the synthesis of nonimmunoglobulin proteins.

Original languageEnglish (US)
Pages (from-to)447-453
Number of pages7
JournalJournal of Cellular Physiology
Volume103
Issue number3
DOIs
Publication statusPublished - Jun 1980

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ASJC Scopus subject areas

  • Physiology
  • Clinical Biochemistry
  • Cell Biology

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