Melanin, radiation, and energy transduction in fungi

Arturo Casadevall, Radames J.B. Cordero, Ruth Bryan, Joshua Nosanchuk, Ekaterina Dadachova

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Melanins are dark pigments that are made by diverse fungi (1, 2). Even fungi that produce white colonies, such as Candida albicans, have the ability to make melanins (3, 4). Melanins have elicited considerable interest in microbial pathogenesis because they are important virulence factors for many pathogenic microbes, and their presence is associated with reduced susceptibility to antifungal drugs (5, 6). Melanins are multifunctional molecules that give cells structural strength as well as reduced susceptibility to temperature extremes, heavy metals, and molecules produced by the immune system such as oxygen- and nitrogen-derived oxidants and microbicidal proteins (2, 7 - 10).

Original languageEnglish (US)
Title of host publicationThe Fungal Kingdom
Publisherwiley
Pages509-514
Number of pages6
ISBN (Electronic)9781683670827
ISBN (Print)9781555819576
DOIs
StatePublished - Sep 5 2017

Keywords

  • Candida albicans
  • Electromagnetic radiation
  • Exobiology
  • Fungi
  • Melanin
  • Metabolic change
  • Radiation-extreme environment
  • Radiotropism

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)

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