Meckel's diverticulum and ectopic epithelium

Evaluation of a complex relationship

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Introduction: Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract. Currently, for any incidentally discovered Meckel's diverticulum, the management approach is based on weighing the statistical odds of future complications against the risks of a diverticulectomy. Materials and Methods: The temporal relationship between age at Meckel's diverticulectomy and the presence of ectopic epithelium was evaluated in our series. A meta-analysis of all reported recent literature on this condition was subsequently performed to evaluate the strength of the relationship between ectopic epithelium and symptomatic Meckel's diverticulum. Results: There was a paucity of ectopic epithelium in Meckel's diverticulectomy specimens in infants operated on at less than 1 year of age. Having two or more ectopic epithelia in a diverticulum does not appear to carry an additive risk for complications. The meta-analysis confirmed that ectopic epithelium was the most significant factor that influenced surgical intervention in all series of Meckel's diverticulum. Conclusion: The relationship between ectopic epithelium and the development of symptomatic Meckel's diverticulum is complex. Further understanding of the development of ectopic rests in the diverticulum will facilitate elucidating the pathophysiology in symptomatic cases.

Original languageEnglish (US)
Pages (from-to)85-89
Number of pages5
JournalJournal of Indian Association of Pediatric Surgeons
Volume19
Issue number2
DOIs
StatePublished - 2014
Externally publishedYes

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Meckel Diverticulum
Epithelium
Diverticulum
Meta-Analysis
Gastrointestinal Tract

Keywords

  • Ectopic epithelium
  • meckel's diverticulum
  • meta-analysis
  • surgical indications

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Meckel's diverticulum and ectopic epithelium : Evaluation of a complex relationship. / Burjonrappa, Sathyaprasad; Khaing, Phue.

In: Journal of Indian Association of Pediatric Surgeons, Vol. 19, No. 2, 2014, p. 85-89.

Research output: Contribution to journalArticle

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